Endocytosis in filamentous Fungi: Coordinating polarized hyphal growth and membrane recycling

IF 2.4 3区生物学 Q3 GENETICS & HEREDITY

Fungal Genetics and Biology Pub Date : 2025-05-12 DOI:10.1016/j.fgb.2025.104000

Caleb Oliver Bedsole , Joseph G. Vasselli , Brian D. Shaw

引用次数: 0

Abstract

Filamentous fungi rely on a finely tuned balance between exocytosis and endocytosis to maintain polarized growth. This review highlights the essential role of the subapical endocytic collar in recycling excess plasma membrane and key proteins, enabling sustained hyphal extension. It distinguishes between clathrin-mediated and AP-2–dependent clathrin-independent pathways, emphasizing their unique contributions to membrane homeostasis and cargo trafficking. The synthesis of quantitative imaging and genetic analyses provides a comprehensive framework for understanding vesicle dynamics, with implications for addressing fungal pathogenicity and industrial applications.

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丝状真菌的内吞作用：协调极化菌丝生长和膜循环

丝状真菌依靠胞吐作用和内吞作用之间的微妙平衡来维持极化生长。这篇综述强调了根尖下内吞环在回收多余的质膜和关键蛋白质，使菌丝持续延伸方面的重要作用。它区分了网格蛋白介导的和ap -2依赖的网格蛋白不依赖的途径，强调了它们对膜稳态和货物运输的独特贡献。定量成像和遗传分析的综合为理解囊泡动力学提供了一个全面的框架，对解决真菌致病性和工业应用具有重要意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Fungal Genetics and Biology 生物-遗传学

CiteScore

6.20

自引率

3.30%

发文量

审稿时长

85 days

期刊介绍： Fungal Genetics and Biology, formerly known as Experimental Mycology, publishes experimental investigations of fungi and their traditional allies that relate structure and function to growth, reproduction, morphogenesis, and differentiation. This journal especially welcomes studies of gene organization and expression and of developmental processes at the cellular, subcellular, and molecular levels. The journal also includes suitable experimental inquiries into fungal cytology, biochemistry, physiology, genetics, and phylogeny. Fungal Genetics and Biology publishes basic research conducted by mycologists, cell biologists, biochemists, geneticists, and molecular biologists. Research Areas include: • Biochemistry • Cytology • Developmental biology • Evolutionary biology • Genetics • Molecular biology • Phylogeny • Physiology.