Dietary fuel or fire: Fatty acids rewire gut ILC3s

IF 25.5 1区医学 Q1 IMMUNOLOGY

Immunity Pub Date : 2025-05-13 DOI:10.1016/j.immuni.2025.04.019

Qixiang Zhao, Changtao Jiang

引用次数: 0

Abstract

Long-term consumption of diets high in fats has detrimental impacts on the immune system, but the window necessary for initiating these effects is unclear. In this issue of Immunity, Xiong et al.¹ demonstrate that even short-term exposure to saturated fats impairs ILC3 function and renders the intestine vulnerable to inflammation and injury.

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饮食燃料或火：脂肪酸重新连接肠道ilc3

长期食用高脂肪饮食对免疫系统有不利影响，但启动这些影响所需的窗口期尚不清楚。在这一期的《免疫》杂志上，Xiong等人1证明，即使短期暴露于饱和脂肪也会损害ILC3的功能，使肠道容易受到炎症和损伤。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Immunity 医学-免疫学

CiteScore

49.40

自引率

2.20%

发文量

205

审稿时长

6 months

期刊介绍： Immunity is a publication that focuses on publishing significant advancements in research related to immunology. We encourage the submission of studies that offer groundbreaking immunological discoveries, whether at the molecular, cellular, or whole organism level. Topics of interest encompass a wide range, such as cancer, infectious diseases, neuroimmunology, autoimmune diseases, allergies, mucosal immunity, metabolic diseases, and homeostasis.