nACh receptors engage a nice ChAT with the liver: B cells serving up regeneration

IF 25.5 1区医学 Q1 IMMUNOLOGY

Immunity Pub Date : 2025-05-13 DOI:10.1016/j.immuni.2025.04.021

Christoph Schultheiß, Mascha Binder

引用次数: 0

Abstract

Liver regeneration is a remarkable and unique biological process, orchestrated by an intricate cellular crosstalk of (non-)parenchymal, immune, and nerve cells. In this issue of Immunity, Modares et al. uncover the pivotal role of choline acetyltransferase (ChAT⁺)-expressing B cells as key orchestrators of liver regeneration.

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nACh受体与肝脏进行良好的ChAT: B细胞提供再生

肝脏再生是一个非凡而独特的生物学过程，由（非）实质细胞、免疫细胞和神经细胞的复杂细胞串扰精心策划。在这一期的《免疫》杂志上，Modares等人揭示了表达胆碱乙酰转移酶（ChAT+）的B细胞作为肝脏再生的关键协调者的关键作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Immunity 医学-免疫学

CiteScore

49.40

自引率

2.20%

发文量

205

审稿时长

6 months

期刊介绍： Immunity is a publication that focuses on publishing significant advancements in research related to immunology. We encourage the submission of studies that offer groundbreaking immunological discoveries, whether at the molecular, cellular, or whole organism level. Topics of interest encompass a wide range, such as cancer, infectious diseases, neuroimmunology, autoimmune diseases, allergies, mucosal immunity, metabolic diseases, and homeostasis.