Effects of an Emotion Regulation Training Programme Combined With Medication Therapy on Mania Severity, Depression and Emotion Regulation Strategies of Adults With Bipolar Disorder Type 1: A Randomized Clinical Trial

IF 3.2 3区心理学 Q1 PSYCHOLOGY, CLINICAL

Clinical psychology & psychotherapy Pub Date : 2025-05-13 DOI:10.1002/cpp.70078

Batoul Tayebi, Abolfazl Ghoreishi, Morteza Kazemi, Parinaz Sadat Amiri Sararoodi, Parnaz Mardani, Seyedeh Elnaz Mousavi

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引用次数: 0

Abstract

Objective

This study aims to investigate the effectiveness of emotion regulation training (ERT) based on Gross's process model combined with medication therapy on mania severity, depression, and emotion regulation of adults with bipolar disorder (BD) type 1.

Methods

This is a randomized, controlled clinical trial on 37 adults (26 females and 11 males) with BD type 1 (depressive phase) assigned to two parallel groups of medication + ERT (n = 19) and medication (n = 18). Their mania, depression, and emotion regulation were measured by the Young mania rating scale (YMRS), the Hamilton depression rating scale (HDRS), and the emotion regulation questionnaire (ERQ) before, immediately after and 3 months after the intervention. The medication therapy included the uptake of mood stabilizers (2–5 tablets of lithium 300 mg, sodium valproate 200 mg and carbamazepine 200 mg) two times per day. The ERT was provided 2 months after receiving mood stabilizers at 8 sessions for 4 weeks, according to Gross's model. After collecting data, they were analysed in SPSS v.26 software.

Results

The difference between the two groups was statistically significant over time in the YMRS (p < 0.001, η² = 0.42) and HDRS (p = 0.007, η² = 0.19) scores, where more significant reductions were reported in the medication + ERT group and maintained for 3 months. Regarding the ERQ score, a significant difference between groups was observed only in the cognitive reappraisal domain (p < 0.001, η² = 0.302) and in the total score (p = 0.001, η² = 0.227) over time, where significant improvements were reported in the medication + ERT group and maintained for 3 months.

Conclusion

The augmentation of medication therapy with the Gross model-based ERT can lead to a higher decrease in mania and depression and an increase in emotion regulation (cognitive reappraisal) of depressed adults with BD type 1.

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情绪调节训练计划联合药物治疗对成人1型双相情感障碍狂躁程度、抑郁和情绪调节策略的影响：一项随机临床试验

目的探讨基于Gross过程模型的情绪调节训练（ERT）结合药物治疗对成人1型双相情感障碍（BD）躁狂症严重程度、抑郁和情绪调节的影响。方法这是一项随机对照临床试验，37名成年BD 1型（抑郁期）患者（26名女性和11名男性）被分为药物+ ERT组（n = 19）和药物组（n = 18）。分别在干预前、干预后和干预后3个月采用杨氏躁狂症评定量表（YMRS）、汉密尔顿抑郁评定量表（HDRS）和情绪调节问卷（ERQ）对患者的躁狂症、抑郁症和情绪调节进行测量。药物治疗包括每日2次服用情绪稳定剂（2-5片锂300 mg，丙戊酸钠200 mg，卡马西平200 mg）。根据Gross的模型，ERT是在接受情绪稳定剂后2个月进行的，共8次，持续4周。收集数据后，用SPSS v.26软件进行分析。结果两组YMRS评分（p < 0.001, η2 = 0.42）和HDRS评分（p = 0.007, η2 = 0.19）随时间变化差异有统计学意义，其中药物+ ERT组下降更显著，并维持3个月。关于ERQ评分，两组间仅在认知重评领域（p < 0.001, η2 = 0.302）和总评分（p = 0.001, η2 = 0.227）随时间的推移有显著差异，其中药物+ ERT组有显著改善，并维持了3个月。结论基于Gross模型的ERT强化药物治疗可使成年抑郁BD 1型患者的躁狂症和抑郁症状明显下降，情绪调节功能（认知重评）增强。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical psychology & psychotherapy PSYCHOLOGY, CLINICAL-

CiteScore

6.30

自引率

5.60%

发文量

106

期刊介绍： Clinical Psychology & Psychotherapy aims to keep clinical psychologists and psychotherapists up to date with new developments in their fields. The Journal will provide an integrative impetus both between theory and practice and between different orientations within clinical psychology and psychotherapy. Clinical Psychology & Psychotherapy will be a forum in which practitioners can present their wealth of expertise and innovations in order to make these available to a wider audience. Equally, the Journal will contain reports from researchers who want to address a larger clinical audience with clinically relevant issues and clinically valid research.