Adenoid cystic carcinoma of the larynx: Case report and review of literature

Q4 Medicine

Radiology Case Reports Pub Date : 2025-05-12 DOI:10.1016/j.radcr.2025.04.071

Fatima Zahra Es-Sahli , Achraf Amine Sbai , Anass Haloui , Drissia Benfadil , Amal Bennani , Azzedine Lachkar , Adil ABDNBI Tsen , Fahd El Ayoubi

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引用次数: 0

Abstract

Adenoid cystic carcinoma (ACC) is a rare malignant neoplasm arising in both major and minor salivary glands. It represents approximately 1% of all head and neck cancers and about 10% of salivary gland tumors. Laryngeal adenoid cystic carcinoma (LACC) is a rare entity that most frequently arises in the subglottic region. It is characterized by slow progression, perineuronal invasion, frequent local recurrences and delayed distant metastasis. Surgical resection remains the gold standard for the treatment of ACC; however, the role of adjuvant radiotherapy and prophylactic neck dissection remains uncertain and is widely debated in the literature.

This case report describes a 60-year-old male patient who presented with progressive dysphagia and worsening dyspnea. Clinical evaluation, including computed tomography (CT), revealed a lesion involving the left glottic and supraglottic regions. Biopsy obtained via direct laryngoscopy confirmed the diagnosis of laryngeal adenoid cystic carcinoma (LACC). The patient subsequently underwent total laryngectomy with adjuvant radiotherapy.

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喉腺样囊性癌：1例报告及文献复习

腺样囊性癌（ACC）是一种发生在大、小唾液腺的罕见恶性肿瘤。它约占所有头颈部癌症的1%，约占唾液腺肿瘤的10%。喉腺样囊性癌（LACC）是一种罕见的实体，最常发生在声门下区域。它的特点是进展缓慢，神经周围浸润，经常局部复发和延迟远处转移。手术切除仍然是治疗ACC的金标准；然而，辅助放疗和预防性颈部清扫的作用仍然不确定，并在文献中广泛争论。本病例报告描述了一位60岁男性患者，他表现为进行性吞咽困难和呼吸困难恶化。临床评估，包括计算机断层扫描（CT），显示病变累及左侧声门和声门上区域。直接喉镜活检证实喉腺样囊性癌（LACC）的诊断。患者随后行全喉切除术和辅助放疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Radiology Case Reports Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

1.10

自引率

0.00%

发文量

1074

审稿时长

30 days

期刊介绍： The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.