Darina Bao , Xin Wang , Chen Zhou , Xiaofei Liu , Yanmei Liu
{"title":"Analysis of the Efficacy of Invasive Mechanical Ventilation in ICU Patients with Severe Heart Failure","authors":"Darina Bao , Xin Wang , Chen Zhou , Xiaofei Liu , Yanmei Liu","doi":"10.1016/j.slast.2025.100302","DOIUrl":null,"url":null,"abstract":"<div><div>In order to study the clinical treatment effect and analyze the main clinical effects of invasive mechanical ventilation in ICU patients with severe heart failure, this paper proposes a efficacy analysis method based on invasive mechanical ventilation for ICU patients with severe heart failure. This study used a retrospective analysis to select 50 patients with severe heart failure admitted to the ICU of a certain hospital from January 2021 to March 2022 as the research subjects, divided into a control group and an observation group. The control group received conventional treatment methods, while the observation group received invasive mechanical ventilation treatment in addition to conventional treatment, and a nursing quality index system was constructed to verify the feasibility and scientificity of the treatment plan. The research results showed that the treatment effectiveness rate of the observation group was 96%, significantly higher than the control group's 84%. In addition, the arterial oxygen saturation (SaO ₂) and partial pressure of oxygen (PaO ₂) in the observation group were significantly increased after treatment compared to the control group, while the partial pressure of carbon dioxide (PaCO ₂) was lower (P<0.05). In addition, in order to improve the comprehensiveness of the analysis, this study further explored the epidemiological characteristics of patients with severe heart failure, including the influence of age, complications (such as diabetes, hypertension, etc.), course characteristics and other factors on the treatment effect. At the same time, an in-depth analysis was conducted on the application strategies of invasive mechanical ventilation in the treatment of severe heart failure, including airway management, ventilator mode optimization, complication prevention, and nursing measures. In addition, this study compared the applicability of invasive and non-invasive mechanical ventilation in the treatment of severe heart failure patients and evaluated the impact of different mechanical ventilation strategies on patient prognosis. To sum up, this study shows that invasive mechanical ventilation can significantly improve the treatment effect of patients with severe heart failure in ICU, improve the oxygenation level and reduce carbon dioxide retention, while optimizing the quality of care and improving the survival rate. The conclusion of this study provides a reference for clinical practice and proposes exploration directions for further optimizing mechanical ventilation strategies in the future.</div></div>","PeriodicalId":54248,"journal":{"name":"SLAS Technology","volume":"32 ","pages":"Article 100302"},"PeriodicalIF":2.5000,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"SLAS Technology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2472630325000603","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
In order to study the clinical treatment effect and analyze the main clinical effects of invasive mechanical ventilation in ICU patients with severe heart failure, this paper proposes a efficacy analysis method based on invasive mechanical ventilation for ICU patients with severe heart failure. This study used a retrospective analysis to select 50 patients with severe heart failure admitted to the ICU of a certain hospital from January 2021 to March 2022 as the research subjects, divided into a control group and an observation group. The control group received conventional treatment methods, while the observation group received invasive mechanical ventilation treatment in addition to conventional treatment, and a nursing quality index system was constructed to verify the feasibility and scientificity of the treatment plan. The research results showed that the treatment effectiveness rate of the observation group was 96%, significantly higher than the control group's 84%. In addition, the arterial oxygen saturation (SaO ₂) and partial pressure of oxygen (PaO ₂) in the observation group were significantly increased after treatment compared to the control group, while the partial pressure of carbon dioxide (PaCO ₂) was lower (P<0.05). In addition, in order to improve the comprehensiveness of the analysis, this study further explored the epidemiological characteristics of patients with severe heart failure, including the influence of age, complications (such as diabetes, hypertension, etc.), course characteristics and other factors on the treatment effect. At the same time, an in-depth analysis was conducted on the application strategies of invasive mechanical ventilation in the treatment of severe heart failure, including airway management, ventilator mode optimization, complication prevention, and nursing measures. In addition, this study compared the applicability of invasive and non-invasive mechanical ventilation in the treatment of severe heart failure patients and evaluated the impact of different mechanical ventilation strategies on patient prognosis. To sum up, this study shows that invasive mechanical ventilation can significantly improve the treatment effect of patients with severe heart failure in ICU, improve the oxygenation level and reduce carbon dioxide retention, while optimizing the quality of care and improving the survival rate. The conclusion of this study provides a reference for clinical practice and proposes exploration directions for further optimizing mechanical ventilation strategies in the future.
期刊介绍:
SLAS Technology emphasizes scientific and technical advances that enable and improve life sciences research and development; drug-delivery; diagnostics; biomedical and molecular imaging; and personalized and precision medicine. This includes high-throughput and other laboratory automation technologies; micro/nanotechnologies; analytical, separation and quantitative techniques; synthetic chemistry and biology; informatics (data analysis, statistics, bio, genomic and chemoinformatics); and more.