Advances of 3D bioprinting technology for periodontal tissue regeneration

IF 4.6 2区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

iScience Pub Date : 2025-04-25 DOI:10.1016/j.isci.2025.112532

Huanhuan Chen , Yu Wang , Yue Lai , Chenda Meng , Xiner Ning , Tianmin Xu , Guangying Song , Yunfan Zhang , Yifan Lin , Bing Han

{"title":"Advances of 3D bioprinting technology for periodontal tissue regeneration","authors":"Huanhuan Chen , Yu Wang , Yue Lai , Chenda Meng , Xiner Ning , Tianmin Xu , Guangying Song , Yunfan Zhang , Yifan Lin , Bing Han","doi":"10.1016/j.isci.2025.112532","DOIUrl":null,"url":null,"abstract":"<div><div>3D bioprinting technology for periodontal tissue regeneration is an advanced manufacturing technique that utilizes three-dimensional (3D) printing principles to fabricate intricate, viable structures that are specifically devised to meet with the demand for the periodontal regeneration. Personalized tissue substitutes through 3D bioprinting possesses the capability to promote tissue regeneration in tissue-defective regions. However, the current 3D bioprinting for periodontal tissue engineering still is confronted with many huge challenges that include selecting the optimal rheological properties for precise printing, ensuring the biocompatibility, and facilitating the consistent cell incorporation. In this review, we introduced the pathogenesis of periodontitis and the principle and categories of 3D bioprinting technology. We provided a comprehensive overview of the latest advancements in the application of cutting-edge biofabrication technology of 3D bioprinting for the overall periodontal regeneration, aiming to provide valuable insights for the optimization of 3D bioprinting technology and potential directions for future clinical application.</div></div>","PeriodicalId":342,"journal":{"name":"iScience","volume":"28 6","pages":"Article 112532"},"PeriodicalIF":4.6000,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"iScience","FirstCategoryId":"103","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S258900422500793X","RegionNum":2,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}

引用次数: 0

Abstract

3D bioprinting technology for periodontal tissue regeneration is an advanced manufacturing technique that utilizes three-dimensional (3D) printing principles to fabricate intricate, viable structures that are specifically devised to meet with the demand for the periodontal regeneration. Personalized tissue substitutes through 3D bioprinting possesses the capability to promote tissue regeneration in tissue-defective regions. However, the current 3D bioprinting for periodontal tissue engineering still is confronted with many huge challenges that include selecting the optimal rheological properties for precise printing, ensuring the biocompatibility, and facilitating the consistent cell incorporation. In this review, we introduced the pathogenesis of periodontitis and the principle and categories of 3D bioprinting technology. We provided a comprehensive overview of the latest advancements in the application of cutting-edge biofabrication technology of 3D bioprinting for the overall periodontal regeneration, aiming to provide valuable insights for the optimization of 3D bioprinting technology and potential directions for future clinical application.

查看原文本刊更多论文

生物3D打印技术在牙周组织再生中的应用进展

用于牙周组织再生的3D生物打印技术是一种先进的制造技术，它利用三维（3D）打印原理来制造复杂的、可行的结构，专门设计用于满足牙周再生的需求。通过3D生物打印的个性化组织替代品具有促进组织缺陷区域组织再生的能力。然而，目前用于牙周组织工程的生物3D打印仍然面临着许多巨大的挑战，包括选择最佳的流变学特性以进行精确打印，确保生物相容性，以及促进细胞的一致结合。本文介绍了牙周炎的发病机制以及生物3D打印技术的原理和分类。本文综述了生物3D打印尖端生物制造技术在牙周整体再生中的应用进展，旨在为生物3D打印技术的优化和未来临床应用的潜在方向提供有价值的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

iScience Multidisciplinary-Multidisciplinary

CiteScore

7.20

自引率

1.70%

发文量

1972

审稿时长

6 weeks

期刊介绍： Science has many big remaining questions. To address them, we will need to work collaboratively and across disciplines. The goal of iScience is to help fuel that type of interdisciplinary thinking. iScience is a new open-access journal from Cell Press that provides a platform for original research in the life, physical, and earth sciences. The primary criterion for publication in iScience is a significant contribution to a relevant field combined with robust results and underlying methodology. The advances appearing in iScience include both fundamental and applied investigations across this interdisciplinary range of topic areas. To support transparency in scientific investigation, we are happy to consider replication studies and papers that describe negative results. We know you want your work to be published quickly and to be widely visible within your community and beyond. With the strong international reputation of Cell Press behind it, publication in iScience will help your work garner the attention and recognition it merits. Like all Cell Press journals, iScience prioritizes rapid publication. Our editorial team pays special attention to high-quality author service and to efficient, clear-cut decisions based on the information available within the manuscript. iScience taps into the expertise across Cell Press journals and selected partners to inform our editorial decisions and help publish your science in a timely and seamless way.