NOTUM-mediated stem cell competition in CRC

IF 72.5 1区医学 Q1 ONCOLOGY

Nature Reviews Cancer Pub Date : 2025-05-12 DOI:10.1038/s41568-025-00827-6

Praver Gupta, Tamal Das

引用次数: 0

Abstract

In this Journal Club. Gupta and Das discuss a study demonstrating how Apc-deficient intestinal stem cells (ISCs) gain a competitive advantage over normal ISCs through the upregulation of NOTUM.

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结直肠癌中notum介导的干细胞竞争

在这个杂志俱乐部。Gupta和Das讨论了一项研究，该研究表明apc缺陷肠干细胞（ISCs）如何通过上调NOTUM而获得比正常ISCs的竞争优势。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Cancer 医学-肿瘤学

CiteScore

111.90

自引率

0.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Cancer, a part of the Nature Reviews portfolio of journals, aims to be the premier source of reviews and commentaries for the scientific communities it serves. The correct abbreviation for abstracting and indexing purposes is Nat. Rev. Cancer. The international standard serial numbers (ISSN) for Nature Reviews Cancer are 1474-175X (print) and 1474-1768 (online). Unlike other journals, Nature Reviews Cancer does not have an external editorial board. Instead, all editorial decisions are made by a team of full-time professional editors who are PhD-level scientists. The journal publishes Research Highlights, Comments, Reviews, and Perspectives relevant to cancer researchers, ensuring that the articles reach the widest possible audience due to their broad scope.