{"title":"Flexing protein assemblies","authors":"Yang Li, Yang Zhang","doi":"10.1038/s41594-025-01560-2","DOIUrl":null,"url":null,"abstract":"Structural flexibility is often considered a challenge in protein design, but it brings opportunities for creating protein assemblies that have several defined structures. A study now suggests that the controllable design of oligomorphic protein assemblies could be achieved by modulating structural flexibility.","PeriodicalId":18822,"journal":{"name":"Nature structural & molecular biology","volume":"38 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature structural & molecular biology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1038/s41594-025-01560-2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Structural flexibility is often considered a challenge in protein design, but it brings opportunities for creating protein assemblies that have several defined structures. A study now suggests that the controllable design of oligomorphic protein assemblies could be achieved by modulating structural flexibility.
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