Recurrent outbreak of Streptococcus bovis/Streptococcus equinus complex-associated meningoencephalitis in farmed mink

IF 0.8 4区农林科学 Q4 PATHOLOGY

Journal of Comparative Pathology Pub Date : 2025-05-01 DOI:10.1016/j.jcpa.2025.04.010

Megan J. Crawford , Kimberley N. Sebastian , Elizabeth Elsmo , Lorelei L. Clarke , Mayra F. Tsoi

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引用次数: 0

Abstract

The Streptococcus bovis/Streptococcus equinus complex (SBSEC) is part of the normal gastrointestinal microflora in animals and humans but is an opportunistic pathogen that has been implicated in meningitis, endocarditis and septicaemia. There is only one report of SBSEC causing disease (endocarditis) in mink. This case report describes two outbreaks of SBSEC infection in farmed mink occurring 1 year apart at the same facility. In both cases, affected mink had neurological signs prior to death and the mortality level was 5,000 (2021) and 500 (2022) out of 100,000 mink. Necropsy findings included hepatomegaly, splenomegaly and congested lungs. Histopathology revealed suppurative meningoencephalitis and neutrophilic inflammation in the lungs, liver and kidneys. Aerobic bacterial culture identified SBSEC isolates in the brain and liver. This is the first report to implicate SBSEC in meningoencephalitis and septicaemia in farmed mink.

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养殖水貂中反复爆发牛链球菌/马链球菌复合体相关脑膜脑炎

牛链球菌/马链球菌复合体（SBSEC）是动物和人类正常胃肠道菌群的一部分，但也是一种与脑膜炎、心内膜炎和败血症有关的机会性病原体。在水貂中，只有一例SBSEC引起的疾病（心内膜炎）的报道。本病例报告描述了在同一设施发生的两次养殖水貂中SBSEC感染的暴发，时间间隔为1年。在这两种情况下，受影响的水貂在死亡前都有神经系统症状，死亡率分别为每10万只水貂中5000只（2021年）和500只（2022年）。尸检结果包括肝肿大、脾肿大和肺充血。组织病理学显示化脓性脑膜脑炎及肺、肝、肾中性粒细胞炎症。需氧细菌培养在脑和肝脏中鉴定出SBSEC分离物。这是第一份将SBSEC与养殖水貂脑膜脑炎和败血症联系起来的报告。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Comparative Pathology 生物-病理学

CiteScore

1.60

自引率

0.00%

发文量

208

审稿时长

50 days

期刊介绍： The Journal of Comparative Pathology is an International, English language, peer-reviewed journal which publishes full length articles, short papers and review articles of high scientific quality on all aspects of the pathology of the diseases of domesticated and other vertebrate animals. Articles on human diseases are also included if they present features of special interest when viewed against the general background of vertebrate pathology.