Botulinum neurotoxin therapy in dystonic head flexion: Anterior injection approaches to the longus colli and longus capitis muscles

IF 2.6 4区 医学 Q2 PHARMACOLOGY & PHARMACY
Lucy Hicklin, Winnie Yeung
{"title":"Botulinum neurotoxin therapy in dystonic head flexion: Anterior injection approaches to the longus colli and longus capitis muscles","authors":"Lucy Hicklin,&nbsp;Winnie Yeung","doi":"10.1016/j.toxicon.2025.108401","DOIUrl":null,"url":null,"abstract":"<div><div>Cervical dystonia with anterocollis is challenging to treat due to involvement of the deep neck muscles, longus colli and longus capitis. Without botulinum neurotoxin injections into these muscles, patient outcomes are often poor. This article outlines two innovative injection techniques developed over many years in our multidisciplinary Neuro-ENT clinic. These have proven to be safe, effective and well-tolerated procedures which can be easily performed in the office with readily available equipment.</div></div>","PeriodicalId":23289,"journal":{"name":"Toxicon","volume":"262 ","pages":"Article 108401"},"PeriodicalIF":2.6000,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Toxicon","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0041010125001758","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0

Abstract

Cervical dystonia with anterocollis is challenging to treat due to involvement of the deep neck muscles, longus colli and longus capitis. Without botulinum neurotoxin injections into these muscles, patient outcomes are often poor. This article outlines two innovative injection techniques developed over many years in our multidisciplinary Neuro-ENT clinic. These have proven to be safe, effective and well-tolerated procedures which can be easily performed in the office with readily available equipment.

Abstract Image

肉毒杆菌神经毒素治疗肌张力障碍头屈曲:前路注射入路至颈长肌和头长肌
颈前颈肌张力障碍由于涉及颈深肌、颈长肌和头长肌而具有挑战性。如果不向这些肌肉注射肉毒杆菌神经毒素,病人的预后往往很差。这篇文章概述了两种创新的注射技术开发多年来在我们的多学科神经-耳鼻喉科诊所。这些已被证明是安全、有效和易于接受的程序,可以在办公室使用现成的设备轻松进行。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Toxicon
Toxicon 医学-毒理学
CiteScore
4.80
自引率
10.70%
发文量
358
审稿时长
68 days
期刊介绍: Toxicon has an open access mirror Toxicon: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. An introductory offer Toxicon: X - full waiver of the Open Access fee. Toxicon''s "aims and scope" are to publish: -articles containing the results of original research on problems related to toxins derived from animals, plants and microorganisms -papers on novel findings related to the chemical, pharmacological, toxicological, and immunological properties of natural toxins -molecular biological studies of toxins and other genes from poisonous and venomous organisms that advance understanding of the role or function of toxins -clinical observations on poisoning and envenoming where a new therapeutic principle has been proposed or a decidedly superior clinical result has been obtained. -material on the use of toxins as tools in studying biological processes and material on subjects related to venom and antivenom problems. -articles on the translational application of toxins, for example as drugs and insecticides -epidemiological studies on envenoming or poisoning, so long as they highlight a previously unrecognised medical problem or provide insight into the prevention or medical treatment of envenoming or poisoning. Retrospective surveys of hospital records, especially those lacking species identification, will not be considered for publication. Properly designed prospective community-based surveys are strongly encouraged. -articles describing well-known activities of venoms, such as antibacterial, anticancer, and analgesic activities of arachnid venoms, without any attempt to define the mechanism of action or purify the active component, will not be considered for publication in Toxicon. -review articles on problems related to toxinology. To encourage the exchange of ideas, sections of the journal may be devoted to Short Communications, Letters to the Editor and activities of the affiliated societies.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信