Safety/Efficacy of a Pusher, Thermal Detachment Coil for Ruptured Intracranial Aneurysms: A Multicenter Real-World Study

IF 2.3 4区医学 Q3 CLINICAL NEUROLOGY

Journal of Neuroimaging Pub Date : 2025-05-09 DOI:10.1111/jon.70050

Antonio Lorenzo, Joaquín Gil, Jose Ignacio Gallego, Alfonso González-Cruz, Fernando Aparici-Robles, Antoni Boscà, Antonio Sagredo, Marc Comas-Cufí, Josep Puig

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Abstract

Background and Purpose

Optima coils are a new type of embolic coils with complex and WAVE shape properties and variable degrees of softness. In patients with ruptured intracranial aneurysms, we examined the safety (periprocedural complications) and efficacy (occlusion rate immediately postprocedure) of the Optima coil.

Methods

We studied 103 consecutive patients with ruptured intracranial aneurysms who were treated exclusively with the Optima coil, without the use of accompanying implanted devices, at five centers in Spain. Endovascular techniques included stand-alone or balloon-assisted coiling. Postprocedural occlusion and periprocedural device-related adverse events were the endpoints. Aneurysm occlusion was graded according to the modified Raymond–Roy Occlusion scale.

Results

Of the 103 enrolled patients (70 female; median age 59 years), 59 (57.3%) presented with an IV Fischer Scale grade, and 61 (59.2%) of the ruptured aneurysms were wide-necked. Thirty-eight (36.9%) aneurysms were located in the anterior communicating artery. Simple-coiling and balloon-assisted coiling were performed in 36 (34.9%) and 65 (63.1%) patients, respectively. Raymond–Roy Class I, II, and III were reached in 64 (60.3%), 29 (28.1%), and ten (9.7%) following the procedure. The periprocedural device-related serious adverse event rate was 12 (13.5%), of which eight (7.7%) were due to coil protrusion. Four (3.8%) patients had intraprocedural aneurysm rupture. No early rebleeding or death was reported.

Conclusion

This analysis suggests that the Optima coil is safe and effective for treating ruptured aneurysms, with satisfactory occlusion rates and low rates of periprocedural device-related serious adverse events.

Abstract Image

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推入式热脱离线圈治疗颅内动脉瘤破裂的安全性/有效性：一项多中心真实世界研究

背景与目的Optima线圈是一种新型的栓塞线圈，具有复杂的波浪形状和不同程度的柔软度。在颅内动脉瘤破裂的患者中，我们检查了Optima线圈的安全性（术中并发症）和有效性（术后立即闭塞率）。方法：我们研究了103例连续的颅内动脉瘤破裂患者，这些患者在西班牙的五个中心只使用Optima线圈治疗，而不使用随附的植入装置。血管内技术包括独立或球囊辅助卷绕。术后闭塞和术中器械相关不良事件为终点。根据改良的Raymond-Roy闭塞量表对动脉瘤闭塞进行分级。结果103例入组患者中，女性70例；中位年龄59岁)，59例（57.3%）为IV Fischer分级，61例（59.2%）为宽颈动脉瘤。38例（36.9%）动脉瘤位于前交通动脉。简单卷取36例（34.9%），球囊辅助卷取65例（63.1%）。64例（60.3%）、29例（28.1%）和10例（9.7%）达到Raymond-Roy I、II和III级。术中器械相关严重不良事件发生率为12例（13.5%），其中线圈突出8例（7.7%）。4例（3.8%）患者发生术中动脉瘤破裂。无早期再出血或死亡报告。结论Optima线圈治疗破裂动脉瘤安全有效，闭塞率满意，术中器械相关严重不良事件发生率低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Neuroimaging 医学-核医学

CiteScore

4.70

自引率

0.00%

发文量

117

审稿时长

6-12 weeks

期刊介绍： Start reading the Journal of Neuroimaging to learn the latest neurological imaging techniques. The peer-reviewed research is written in a practical clinical context, giving you the information you need on: MRI CT Carotid Ultrasound and TCD SPECT PET Endovascular Surgical Neuroradiology Functional MRI Xenon CT and other new and upcoming neuroscientific modalities.The Journal of Neuroimaging addresses the full spectrum of human nervous system disease, including stroke, neoplasia, degenerating and demyelinating disease, epilepsy, tumors, lesions, infectious disease, cerebral vascular arterial diseases, toxic-metabolic disease, psychoses, dementias, heredo-familial disease, and trauma.Offering original research, review articles, case reports, neuroimaging CPCs, and evaluations of instruments and technology relevant to the nervous system, the Journal of Neuroimaging focuses on useful clinical developments and applications, tested techniques and interpretations, patient care, diagnostics, and therapeutics. Start reading today!