X-ray interaction and computational characterization and analysis of human brain tissuefor applications in cancer detection

IF 2.6 3区工程技术 Q1 NUCLEAR SCIENCE & TECHNOLOGY

Nuclear Engineering and Technology Pub Date : 2025-05-02 DOI:10.1016/j.net.2025.103683

Aysun Böke

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引用次数: 0

Abstract

This study covers the 1–140 keV energy region, which includes the photoelectric effect, coherent (Rayleigh) and incoherent (Compton) scattering. The study was conducted by testing the different elemental contents from the literature regarding the molecular structure of the human brain grey and white matter. The elemental content most compatible with the experimental results was determined. Using this elemental content, the atomic cross-sections were calculated. The investigated molecular cross-sections and attenuation coefficients were then determined using the relevant atomic cross-sections. The differential coherent scattering distribution for an energy value of 6.935 keV was found to be in very good agreement with its experimental counterparts. The total attenuation coefficients were also in excellent agreement (0,1–3,52 % for grey matter and 0,05–4,47 % for white matter) with experimental data above 28 keV. This study is new in that it examines the grey and white matter of the human brain tissue separately, calculating interaction cross-sections and attenuation coefficients via numerical integration in atomic and molecular form, including very low energy regions. This study will give an idea about the effect of normal brain tissue for applications of cancer detection in radiation oncology and radiology.

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人脑组织的x射线相互作用和计算表征与分析在癌症检测中的应用

本研究涵盖了1-140 keV的能量区域，包括光电效应、相干（瑞利）散射和非相干（康普顿）散射。这项研究是通过测试文献中关于人类大脑灰质和白质分子结构的不同元素含量来进行的。测定了最符合实验结果的元素含量。利用这一元素含量，计算了原子截面。然后用相关的原子截面确定所研究的分子截面和衰减系数。能量值为6.935 keV时的微分相干散射分布与实验结果非常吻合。总衰减系数（灰质为0,1 - 3,52%，白质为0,05 - 4,47%）与28 keV以上的实验数据也非常吻合。这项研究的新颖之处在于，它分别检查了人脑组织的灰质和白质，通过原子和分子形式的数值积分计算相互作用截面和衰减系数，包括非常低的能量区域。本研究将为正常脑组织在放射肿瘤学和放射学中癌症检测的应用提供一个思路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nuclear Engineering and Technology 工程技术-核科学技术

CiteScore

4.80

自引率

7.40%

发文量

431

审稿时长

3.5 months

期刊介绍： Nuclear Engineering and Technology (NET), an international journal of the Korean Nuclear Society (KNS), publishes peer-reviewed papers on original research, ideas and developments in all areas of the field of nuclear science and technology. NET bimonthly publishes original articles, reviews, and technical notes. The journal is listed in the Science Citation Index Expanded (SCIE) of Thomson Reuters. NET covers all fields for peaceful utilization of nuclear energy and radiation as follows: 1) Reactor Physics 2) Thermal Hydraulics 3) Nuclear Safety 4) Nuclear I&C 5) Nuclear Physics, Fusion, and Laser Technology 6) Nuclear Fuel Cycle and Radioactive Waste Management 7) Nuclear Fuel and Reactor Materials 8) Radiation Application 9) Radiation Protection 10) Nuclear Structural Analysis and Plant Management & Maintenance 11) Nuclear Policy, Economics, and Human Resource Development