Proton imaging at the end of the proton range

IF 2.8 3区 物理与天体物理 Q3 CHEMISTRY, PHYSICAL
F.L.S. Cerutti , V.V. Denyak , S.A. Paschuk , H.R. Schelin , J.A.P. Setti , J.T. Assis
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Abstract

Since the earliest studies on the usage of protons for image production, it was declared that to take advantage of proton beam it is necessary to choose an initial proton energy close to the minimum possible value, i.e., to work at the end of the proton range, where the proton flux changes very steeply. However, this idea was declared, but was not investigated. In the present work, we study the efficiency of image production at the end of the proton range with the three physical observables that can be used for such purpose: the mean energy of exit proton, number of protons and total energy of exit protons. By using a Monte Carlo simulation, we studied the uncertainties in the determination of object thickness with these observables at the conditions typical for medical imaging. At the area before the end of the proton range, the uncertainty in thickness determination obtained analysing the mean energy of exit proton is significantly less than the uncertainty obtained for the number of protons. At the end of the range, the number of protons becomes preferable for the measurement of the absorber thickness. The precision of the total energy of exit protons matches the precision of the number of protons at the end of the range and the precision of the mean energy of exit proton outside this region. Any effect that justifies the idea to work at the end of the proton range was not observed.
质子成像在质子范围的末端
从最早关于利用质子进行成像的研究开始,就有人宣称,要利用质子束,必须选择接近最小可能值的初始质子能量,即在质子范围的末端工作,在那里质子通量变化非常大。然而,这个想法被宣布了,但没有被调查。在本工作中,我们研究了在质子范围末端产生图像的效率,这三个物理观测值可用于此目的:出口质子的平均能量,质子数和出口质子的总能量。通过蒙特卡罗模拟,我们研究了在典型的医学成像条件下,这些观测值在确定物体厚度时的不确定性。在质子范围结束前的区域,分析出口质子的平均能量得到的厚度测定的不确定度明显小于质子数得到的不确定度。在该范围的末端,质子数对于吸收体厚度的测量更为可取。退出质子总能量的精度与范围末端质子数的精度和该区域外退出质子平均能量的精度相匹配。没有观察到任何证明在质子范围的末端工作的想法是正确的效应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Radiation Physics and Chemistry
Radiation Physics and Chemistry 化学-核科学技术
CiteScore
5.60
自引率
17.20%
发文量
574
审稿时长
12 weeks
期刊介绍: Radiation Physics and Chemistry is a multidisciplinary journal that provides a medium for publication of substantial and original papers, reviews, and short communications which focus on research and developments involving ionizing radiation in radiation physics, radiation chemistry and radiation processing. The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. This could include papers that are very similar to previous publications, only with changed target substrates, employed materials, analyzed sites and experimental methods, report results without presenting new insights and/or hypothesis testing, or do not focus on the radiation effects.
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