Investigation of striped acoustic field modulation in microchannels based on holographic acoustofluidic chips

IF 3.8 2区物理与天体物理 Q1 ACOUSTICS

Ultrasonics Pub Date : 2025-05-03 DOI:10.1016/j.ultras.2025.107685

Luming Li , Mingyong Zhou , Lei Huang , Kai Luo , Linghan Shen , Bingyan Jiang

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引用次数: 0

Abstract

Accurate modulation of striped standing wave acoustic field in microchannels is of great significance for applications in biochemistry. In this work, the regulatory mechanism of the striped acoustic field in microchannels modulated by a holographic acoustofluidic chip with oblique microstructures was investigated. The effects of microstructure and acoustic wave parameters on the spacing of acoustic pressure node lines were studied. The error between the simulated and experimental results was less than 5 %. A mathematical model was established and confirmed to regulate the acoustic pressure node line spacing. The spacing of acoustic pressure node lines is found to be negatively correlated with both the inclination angle of the microstructure and the frequency of the incident wave. By selecting appropriate values for the inclination angle and frequency based on modulation effects and application requirements, a regulatory scope of approximately 55–250 μm for the acoustic pressure node line spacing can be achieved in microchannel. The model established and the conclusions drawn from this work can provide valuable guidance for particle sorting, analysis, and tissue engineering applications based on acoustofluidic chips.

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基于全息声流芯片的微通道条纹声场调制研究

微通道中条纹驻波声场的精确调制在生物化学中的应用具有重要意义。本文研究了斜向微结构全息声流控芯片调制微通道条纹声场的调节机制。研究了微观结构和声波参数对声压节点线间距的影响。模拟结果与实验结果的误差小于5%。建立并验证了调节声压节点线间距的数学模型。声压节点线间距与微结构倾角和入射波频率均呈负相关。根据调制效果和应用需求选择合适的倾角和频率值，可实现微通道中声压节点线间距约为55 ~ 250 μm的调节范围。所建立的模型和所得结论对基于声流控芯片的颗粒分选、分析和组织工程应用具有重要的指导意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ultrasonics 医学-核医学

CiteScore

7.60

自引率

19.00%

发文量

186

审稿时长

3.9 months

期刊介绍： Ultrasonics is the only internationally established journal which covers the entire field of ultrasound research and technology and all its many applications. Ultrasonics contains a variety of sections to keep readers fully informed and up-to-date on the whole spectrum of research and development throughout the world. Ultrasonics publishes papers of exceptional quality and of relevance to both academia and industry. Manuscripts in which ultrasonics is a central issue and not simply an incidental tool or minor issue, are welcomed. As well as top quality original research papers and review articles by world renowned experts, Ultrasonics also regularly features short communications, a calendar of forthcoming events and special issues dedicated to topical subjects.