Visual and refractive outcomes of photorefractive keratectomy in hyperopia and hyperopic-astigmatism: A systematic review and meta-analysis

IF 2.6 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-04-24 DOI:10.1016/j.pdpdt.2025.104604

Samira Hassanzadeh , Firouzeh Fereydouni , Elham Bakhtiari

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引用次数: 0

Abstract

Purpose: To evaluate the Visual and Refractive outcomes of Photorefractive Keratectomy(PRK) in Patients with Hyperopia and Hyperopic-astigmatism

Methods: This meta-analysis followed the PRISMA statement. Literature search of databases including PubMed, web of science, Scopus, Medline, Cochrane library and Google-Scholar was done to find relevant published articles about outcomes of PRK surgery for hyperopic and compound hyperopic-astigmatism. The search was conducted with no time or language restriction; and was updated until 31th December 2023. Open Meta Analyst software was used for data analysis. The combined effect of continuous data was presented by mean difference and 95 % confidence interval (CI).

Results: A total of 750 eyes from 481 patients (49.5 % female and 50.5 % male) were analyzed. The postoperative improvement in UCVA(uncorrected visual acuity), SE(spherical equivalent) and cylindrical power in these samples were statistically significant(P = 0.001). The overall incidence of corneal haze was 32.5 %(95 % CI:[26.5 %, 38.4 %]).

Conclusions: The Visual and Refractive outcomes of PRK in Patients with Hyperopia and Hyperopic-astigmatism are satisfactory, but its 32.5 % haze incidence is significantly higher than in myopic PRK and Trans-PRK(trans-epithelial PRK), raising safety concerns. Further research is needed to reduce haze and enhance outcomes.

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屈光性角膜切除术治疗远视和远视散光的视力和屈光效果：系统回顾和荟萃分析

目的：评价远视和远视散光患者的光屈光性角膜切除术（PRK）的视力和屈光效果。方法：本荟萃分析遵循PRISMA声明。对PubMed、web of science、Scopus、Medline、Cochrane library、Google-Scholar等数据库进行文献检索，查找PRK手术治疗远视和复合远视散光的相关文献。搜查没有时间和语言限制；并更新至2023年12月31日。使用Open Meta Analyst软件进行数据分析。连续资料的联合效应用均值差和95%置信区间（CI）表示。结果：共分析481例患者750只眼，其中女性49.5%，男性50.5%。术后未矫正视力（UCVA）、球形等效视力（SE）和圆柱形放大率的改善均有统计学意义（P = 0.001）。角膜混浊的总发生率为32.5% （95% CI:[26.5%, 38.4%]）。结论：PRK治疗远视和远视散光患者的视力和屈光结果令人满意，但其32.5%的雾霾发生率明显高于近视PRK和Trans-PRK（跨上皮PRK），引起安全性担忧。需要进一步的研究来减少雾霾并提高效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.