Comparative examination of the chemistry and biology of AI-driven gold NPs in Theranostics: New insights into biosensing, bioimaging, genomics, diagnostics, and therapy

IF 4.2 2区医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL

Nanomedicine : nanotechnology, biology, and medicine Pub Date : 2025-04-28 DOI:10.1016/j.nano.2025.102821

Donya Esmaeilpour MSc , Ehsan Nazarzadeh Zare PhD , Mahnaz Hassanpur MSc , Farooq Sher PhD , Mika Sillanpää PhD

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Abstract

Integrating artificial intelligence (AI) with nanomedicine is transforming Theranostics, driving advances in biosensing, bioimaging, genomics, diagnostics, and treatment. This review highlights the latest advancements in AI-driven nanomedicine, focusing on its transformative impact on healthcare. AI-integrated biosensors offer ultra-sensitive, real-time biomaterial detection, reducing false positives by 40 %. In bioimaging, AI algorithms improve resolution to 10 nm, particularly in gold nanoparticles (AuNP)-based imaging. AuNPs, leveraging surface plasmon resonance (SPR), act as contrast agents for early disease detection. AI accelerates genomic analysis, increasing sequencing accuracy by 30 %, enhancing biomarker identification for personalized medicine. AI powered diagnostics ensure rapid, non-invasive pathogen detection within 30 min with 95 % accuracy. AI-driven drug delivery systems enable precise, controlled release, reducing side effects by 20 %. This review explores AI-enhanced AuNPs in biosensing, bioimaging, genomics, diagnostics, and therapy while addressing challenges like scalability, biocompatibility. AI's role in Nanomedicine underscores its potential to revolutionize personalized medicine and future healthcare innovations.

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人工智能驱动的金NPs在治疗学中的化学和生物学比较研究：对生物传感、生物成像、基因组学、诊断和治疗的新见解

人工智能（AI）与纳米医学的结合正在改变治疗学，推动生物传感、生物成像、基因组学、诊断和治疗领域的进步。本文重点介绍了人工智能驱动的纳米医学的最新进展，重点介绍了其对医疗保健的变革性影响。人工智能集成的生物传感器提供超灵敏、实时的生物材料检测，将误报率降低40%。在生物成像中，人工智能算法将分辨率提高到10纳米，特别是在基于金纳米颗粒（AuNP）的成像中。AuNPs利用表面等离子体共振（SPR）作为早期疾病检测的造影剂。人工智能加速了基因组分析，将测序准确性提高了30%，增强了个性化医疗的生物标志物识别。人工智能驱动的诊断确保在30分钟内快速，无创的病原体检测，准确率为95%。人工智能驱动的药物输送系统可以实现精确、可控的释放，将副作用减少20%。本文探讨了人工智能增强的aunp在生物传感、生物成像、基因组学、诊断和治疗方面的应用，同时解决了可扩展性、生物相容性等挑战。人工智能在纳米医学中的作用凸显了其革命性的个性化医疗和未来医疗保健创新的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nanomedicine : nanotechnology, biology, and medicine 工程技术-纳米科技

CiteScore

11.10

自引率

0.00%

发文量

133

审稿时长

42 days

期刊介绍： The mission of Nanomedicine: Nanotechnology, Biology, and Medicine (Nanomedicine: NBM) is to promote the emerging interdisciplinary field of nanomedicine. Nanomedicine: NBM is an international, peer-reviewed journal presenting novel, significant, and interdisciplinary theoretical and experimental results related to nanoscience and nanotechnology in the life and health sciences. Content includes basic, translational, and clinical research addressing diagnosis, treatment, monitoring, prediction, and prevention of diseases.