An AuNP-based Indicator for Rapid On-Site Detection of Strontium ion

IF 12.2 1区环境科学与生态学 Q1 ENGINEERING, ENVIRONMENTAL

Journal of Hazardous Materials Pub Date : 2025-05-07 DOI:10.1016/j.jhazmat.2025.138525

Zhen Dong, Yanying Wang, Xianming Li, Peng Wu

{"title":"An AuNP-based Indicator for Rapid On-Site Detection of Strontium ion","authors":"Zhen Dong, Yanying Wang, Xianming Li, Peng Wu","doi":"10.1016/j.jhazmat.2025.138525","DOIUrl":null,"url":null,"abstract":"Strontium (Sr) has attracted significant attention due to its radioactivity and physiological toxicity. Rapid and precise detection of Sr2+ was critical for risk mitigation, particularly in accidents involving strontium leaks. However, the existing methods often compromise accuracy, speed, and user-friendliness, making on-site detection of Sr2+ challenging. Herein, we developed a gold nanoparticle (AuNP)-based indicator for Sr2+ through leveraging high-affinity binding between Sr2+ and G-quadruplex (G4) DNA to regulate the thioflavin T (ThT)-induced charge neutralization assembly of AuNPs. The proposed indicator achieved a detection limit of 2.5 nM, significantly lower than the maximum allowable concentration of Sr2+ in drinking water (17.1 μM). To enable on-site detection of Sr2+, we designed a self-constructed portable suitcase housing all necessary components of the indicator (~0.14 $ per test), and a smartphone app for colorimetric analysis. The proposed indicator was successfully explored for on-site detection of Sr2+ in rivers across Chengdu, Kunming, and Xishuangbanna, China, demonstrating its reliability for environmental monitoring.","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"3 1","pages":""},"PeriodicalIF":12.2000,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Hazardous Materials","FirstCategoryId":"93","ListUrlMain":"https://doi.org/10.1016/j.jhazmat.2025.138525","RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, ENVIRONMENTAL","Score":null,"Total":0}

引用次数: 0

Abstract

Strontium (Sr) has attracted significant attention due to its radioactivity and physiological toxicity. Rapid and precise detection of Sr²⁺ was critical for risk mitigation, particularly in accidents involving strontium leaks. However, the existing methods often compromise accuracy, speed, and user-friendliness, making on-site detection of Sr²⁺ challenging. Herein, we developed a gold nanoparticle (AuNP)-based indicator for Sr²⁺ through leveraging high-affinity binding between Sr²⁺ and G-quadruplex (G4) DNA to regulate the thioflavin T (ThT)-induced charge neutralization assembly of AuNPs. The proposed indicator achieved a detection limit of 2.5 nM, significantly lower than the maximum allowable concentration of Sr²⁺ in drinking water (17.1 μM). To enable on-site detection of Sr²⁺, we designed a self-constructed portable suitcase housing all necessary components of the indicator (~0.14 $ per test), and a smartphone app for colorimetric analysis. The proposed indicator was successfully explored for on-site detection of Sr²⁺ in rivers across Chengdu, Kunming, and Xishuangbanna, China, demonstrating its reliability for environmental monitoring.

Abstract Image

查看原文本刊更多论文

一种基于aunp的锶离子快速现场检测指标

锶（Sr）由于其放射性和生理毒性引起了人们的广泛关注。快速和精确地检测Sr2+对于减轻风险至关重要，特别是在涉及锶泄漏的事故中。然而，现有的方法往往会降低准确性、速度和用户友好性，使得Sr2+的现场检测具有挑战性。在此，我们开发了一种基于金纳米颗粒（AuNP）的Sr2+指示剂，利用Sr2+与g -四重体（G4） DNA之间的高亲和力结合来调节硫黄素T （ThT）诱导的AuNPs电荷中和组装。该指标的检出限为2.5 nM，显著低于饮用水中Sr2+的最大允许浓度（17.1 μM）。为了实现Sr2+的现场检测，我们设计了一个自建的便携式手提箱，其中包含所有必需的指示剂组件（每次测试约0.14美元），以及一个用于比色分析的智能手机应用程序。该指标在成都、昆明、西双版纳等地的河流Sr2+现场检测中获得成功，验证了该指标在环境监测中的可靠性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Hazardous Materials 工程技术-工程：环境

CiteScore

25.40

自引率

5.90%

发文量

3059

审稿时长

58 days

期刊介绍： The Journal of Hazardous Materials serves as a global platform for promoting cutting-edge research in the field of Environmental Science and Engineering. Our publication features a wide range of articles, including full-length research papers, review articles, and perspectives, with the aim of enhancing our understanding of the dangers and risks associated with various materials concerning public health and the environment. It is important to note that the term "environmental contaminants" refers specifically to substances that pose hazardous effects through contamination, while excluding those that do not have such impacts on the environment or human health. Moreover, we emphasize the distinction between wastes and hazardous materials in order to provide further clarity on the scope of the journal. We have a keen interest in exploring specific compounds and microbial agents that have adverse effects on the environment.