Historical evolution, hotspots, and trends in tendon tissue engineering: A bibliometric analysis

IF 3.5 3区环境科学与生态学 Q3 CELL & TISSUE ENGINEERING

Regenerative Therapy Pub Date : 2025-05-06 DOI:10.1016/j.reth.2025.04.009

Wenlong Hou , Wenwen Liu , Mengtian Tan , Jiaxu Fang , Keye Cao , Xincheng Du , Haijun Zhang

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引用次数: 0

Abstract

Introduction

As a significant branch of tissue engineering, tendon tissue engineering has developed rapidly, driven by advancements in new technologies and the refinement of medical theories. This study summarizes its development by analyzing historical evolution, research hotspots, and future trends to reveal core research directions and potential pathways.

Methods

Based on literature from WoS CC (1991–2024) and analyzed using VOSviewer, CiteSpace, and Bibliometrix, the study evaluates publication trends and research patterns.

Results

Findings show continuous growth in annual publications. The United States and China are key contributors with close collaboration. Chang James is the most prolific author, and stable research teams have emerged, though inter-team cooperation remains limited. Acta Biomaterialia publishes the most papers in this field, characterized by interdisciplinary integration. Key research focuses include scaffolds, seed cells, and rotator cuff injuries. Frontiers involve ideal scaffold construction, tendon adhesion prevention, and regeneration strategies. Future directions emphasize novel biomaterials, tendon-bone interface healing, innovative seed cell cultivation, tendon growth microenvironment construction, and clinical translation of research outcomes.

Conclusion

This bibliometric analysis reveals the core research directions and potential pathways in tendon tissue engineering, providing a reference for future studies.

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肌腱组织工程的历史演变、热点和趋势：文献计量学分析

肌腱组织工程作为组织工程的一个重要分支，在新技术的进步和医学理论的完善的推动下，发展迅速。本研究通过分析其历史沿革、研究热点和未来趋势，总结其发展历程，揭示核心研究方向和潜在路径。方法以1991-2024年WoS CC文献为基础，利用VOSviewer、CiteSpace、Bibliometrix等软件分析文献发表趋势和研究模式。结果：年度出版物数量持续增长。美国和中国是密切合作的主要贡献者。张詹姆斯是最多产的作者，并且出现了稳定的研究团队，但团队间的合作仍然有限。Acta biomateralia是该领域发表论文最多的期刊，具有跨学科整合的特点。主要研究重点包括支架、种子细胞和肩袖损伤。前沿研究包括理想支架结构、肌腱粘连预防和再生策略。未来的发展方向是新型生物材料、肌腱-骨界面愈合、创新种子细胞培养、肌腱生长微环境构建以及研究成果的临床转化。结论通过文献计量学分析揭示了肌腱组织工程的核心研究方向和潜在途径，为今后的研究提供参考。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Regenerative Therapy Engineering-Biomedical Engineering

CiteScore

6.00

自引率

2.30%

发文量

106

审稿时长

49 days

期刊介绍： Regenerative Therapy is the official peer-reviewed online journal of the Japanese Society for Regenerative Medicine. Regenerative Therapy is a multidisciplinary journal that publishes original articles and reviews of basic research, clinical translation, industrial development, and regulatory issues focusing on stem cell biology, tissue engineering, and regenerative medicine.