Multimodal bioelectronics: A pathway to digital health management

Abstract

Recent advancements in multimodal bioelectronics have demonstrated remarkable promise in transforming digital health. In contrast to conventional hospital-based healthcare systems, multimodal bioelectronics facilitates flexible and continuous physiological monitoring, offering the potential for accurate diagnosis and personalized therapeutics. In this review, we summarize and highlight the latest progress in multimodal bioelectronics and their practical applications. We first introduce emerging material selections and interface design strategies for conformal contact with the human body. Then, we discuss the principles of energy management and the workflow of integrated platforms, especially introducing algorithm utilization for real-time data acquisition, processing, and transmission. Additionally, we focus on the categorized practical applications of multimodal bioelectronics in digital health by emphasizing their role in the healthcare of specific populations, as well as in the diagnosis and monitoring of common diseases. Finally, we provide an outlook to address the challenges and the trends of multimodal bioelectronics toward digital health management.