Impact of intraoperative NBI on complete resections and recurrence in oral and oropharyngeal cancer

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

American Journal of Otolaryngology Pub Date : 2025-05-06 DOI:10.1016/j.amjoto.2025.104630

Francesca Boscolo Nata , Rossana Bussani , Egidio Sia , Fabiola Giudici , Paolo Boscolo-Rizzo , Giancarlo Tirelli

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Abstract

Purpose

The aim of this study was to assess the number of complete resections and recurrence rates in oral and oropharyngeal squamous cell carcinoma treated with intraoperative narrow-band-imaging.

Materials and methods

In this observational study, superficial resection margins of oral and oropharyngeal squamous cell carcinoma were intraoperatively defined using narrow-band-imaging. The number of complete resections was assessed. Patients were followed up for at least 5 years: disease free survival and the cumulative incidence of local recurrence were recorded.

Results

93 squamous cell carcinoma were considered. Surgical resection was complete in 84.9 % of cases. The 5-years disease free survival was 76.2 % (95%CI: 67.1 %–84.4 %). Cumulative incidence of local recurrence was 9.7 % (95%CI: 4.7 %–16.7 %), lower compared to previous literature: it was higher in patients over 68 years (14.3 %, 95%CI: 6.2 %–25.6 % vs 4.5 %, 95%CI: 0.8 %–13.8 %) although without statistically significance.

Conclusions

In oral and oropharyngeal squamous cell carcinoma surgery, narrow-band imaging is a valuable tool for accurately identifying the true superficial extent of the tumor, facilitating complete resection and potentially reducing local recurrence.

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术中NBI对口腔癌和口咽癌完全切除和复发的影响

目的评价术中窄带显像治疗口腔及口咽鳞状细胞癌的完全切除次数和复发率。材料和方法在这项观察性研究中，术中使用窄带成像确定口腔和口咽鳞状细胞癌的浅表切除边缘。评估完全切除的数量。随访至少5年，记录无病生存期和局部复发累计发生率。结果93例为鳞状细胞癌。手术切除成功率为84.9%。5年无病生存率为76.2% （95%CI: 67.1% ~ 84.4%）。累积局部复发率为9.7% (95%CI: 4.7% - 16.7%)，低于既往文献；68岁以上患者的累积局部复发率较高（14.3%,95%CI: 6.2% - 25.6% vs 4.5%, 95%CI: 0.8% - 13.8%），但无统计学意义。结论在口腔及口咽鳞状细胞癌手术中，窄带成像是准确识别肿瘤表面真实范围、促进肿瘤完全切除和减少局部复发的重要工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Otolaryngology 医学-耳鼻喉科学

CiteScore

4.40

自引率

4.00%

发文量

378

审稿时长

41 days

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