Cortical activity during the first 4 months after anterior cruciate ligament reconstruction while performing an active knee joint position sense test: A pilot study

IF 1.6 4区医学 Q3 ORTHOPEDICS

Knee Pub Date : 2025-05-07 DOI:10.1016/j.knee.2025.04.017

Daniela Nyffenegger , Heiner Baur , Philipp Henle , Aglaja Busch

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引用次数: 0

Abstract

Background

Anterior cruciate ligament (ACL) rupture is thought to alter the way in which the brain receives and processes information, affecting body movements. Although alterations in brain activity after ACL rupture have been described, these are limited to time points more than 6 months after rupture. Therefore, this pilot study aims to investigate cortical activity during an active knee joint position sense (JPS) test within the first 4 months after ACL reconstruction.

Methods

Twelve participants with ACL reconstruction (nine males; age 25.3 ± 6.4 years; height 173.6 ± 8.0 cm; mass 71.1 ± 9.1 kg) and 12 matched healthy controls (nine males; age 28.8 ± 9.7 years; height 174.5 ± 9.7 cm; mass 72.7 ± 12.7 kg) performed an active knee JPS test in an open kinetic chain with a starting angle of 90° knee flexion and a target angle of 50°. Absolute angular error was measured with an electrogoniometer. Cortical activity was simultaneously recorded with dry electroencephalography. Participants with ACL reconstruction were measured at 5–8 weeks postoperative (M1) and 12–16 weeks postoperative (M2), the control group once. Power spectra for the frequencies, theta (4.75–6.75 Hz), alpha-1 (7.0–9.5 Hz) and alpha-2 (9.75–12.5 Hz) for frontal, central and parietal regions of interest were calculated.

Results

Participants with ACL reconstruction exhibited significantly higher central theta power during JPS testing with their uninvolved leg at M1 compared with M2 (adjusted P = 0.01; rank epsilon squared = 0.39). No other comparisons yielded statistically significant differences.

Conclusions

The results cautiously support current evidence on cortical alterations following ACL reconstruction. A larger sample size and more measurement time points may provide further insight into possible alterations in the early postoperative period.

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前交叉韧带重建后头4个月的皮质活动，同时进行主动膝关节位置感测试：一项试点研究

前交叉韧带（ACL）断裂被认为会改变大脑接收和处理信息的方式，影响身体运动。虽然描述了前交叉韧带破裂后大脑活动的改变，但这些改变仅限于破裂后6个月以上的时间点。因此，本初步研究旨在调查前4个月ACL重建后主动膝关节位置感（JPS）测试期间的皮质活动。方法12例ACL重建患者(男性9例；年龄25.3±6.4岁；高度173.6±8.0 cm；体重71.1±9.1 kg)和12名匹配的健康对照组(9名男性；年龄28.8±9.7岁；高度174.5±9.7 cm；质量72.7±12.7 kg)在开放的运动链中进行主动膝关节JPS测试，起始角度为膝关节屈曲90°，目标角度为50°。用电测角仪测量绝对角误差。同时用干性脑电图记录皮层活动。ACL重建的参与者分别在术后5-8周（M1）和12-16周（M2）测量，对照组1次。计算额叶、中央和顶叶感兴趣区域的theta （4.75-6.75 Hz）、alpha-1 （7.0-9.5 Hz）和alpha-2 （9.75-12.5 Hz）频率的功率谱。结果前交叉韧带重建者在M1未受损伤腿的JPS测试中表现出显著高于M2的中央θ波功率(调整后P = 0.01；秩平方= 0.39)。其他比较没有产生统计学上的显著差异。结论本研究结果谨慎地支持了前交叉韧带重建后皮层改变的现有证据。更大的样本量和更多的测量时间点可以进一步了解术后早期可能发生的变化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Knee 医学-外科

CiteScore

3.80

自引率

5.30%

发文量

171

审稿时长

6 months

期刊介绍： The Knee is an international journal publishing studies on the clinical treatment and fundamental biomechanical characteristics of this joint. The aim of the journal is to provide a vehicle relevant to surgeons, biomedical engineers, imaging specialists, materials scientists, rehabilitation personnel and all those with an interest in the knee. The topics covered include, but are not limited to: • Anatomy, physiology, morphology and biochemistry; • Biomechanical studies; • Advances in the development of prosthetic, orthotic and augmentation devices; • Imaging and diagnostic techniques; • Pathology; • Trauma; • Surgery; • Rehabilitation.