Insecticide resistance in mosquitoes: molecular mechanisms, management, and alternatives

IF 4.1 1区 农林科学 Q1 ENTOMOLOGY
Hemanga Hazarika, Ravi Kumar Rajan, Padmanath Pegu, Punamjyoti Das
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引用次数: 0

Abstract

Insecticides remain a primary tool in mosquito-borne disease control; however, the resistance in mosquito populations poses a significant challenge to the efficacy. Resistance mechanisms, including target sites mutations and increase in metabolic detoxification, have emerged due to wide spread insecticide use. The growing resistance to pyrethroids used in long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) necessitates alternative control strategies. Furthermore, synthetic insecticides often negatively impact the environment and nontarget organisms, highlighting the necessity of exploring alternative pest management strategies. Biological control methods utilizing natural predators, pathogens, and parasites of mosquitoes have shown promise as viable alternatives to traditional insecticide approaches.

蚊子的杀虫剂抗性:分子机制、管理和替代方法
杀虫剂仍然是控制蚊媒疾病的主要工具;然而,蚊虫种群的抗药性对药效构成了重大挑战。由于杀虫剂的广泛使用,抗性机制,包括靶点突变和代谢解毒的增加,已经出现。长效杀虫蚊帐和室内滞留喷洒中使用的拟除虫菊酯抗药性日益增强,因此需要采取其他控制策略。此外,合成杀虫剂往往对环境和非目标生物产生负面影响,因此有必要探索其他有害生物管理战略。利用蚊子的天敌、病原体和寄生虫的生物防治方法有望成为传统杀虫剂的可行替代方法。
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来源期刊
Journal of Pest Science
Journal of Pest Science 生物-昆虫学
CiteScore
10.40
自引率
8.30%
发文量
114
审稿时长
6-12 weeks
期刊介绍: Journal of Pest Science publishes high-quality papers on all aspects of pest science in agriculture, horticulture (including viticulture), forestry, urban pests, and stored products research, including health and safety issues. Journal of Pest Science reports on advances in control of pests and animal vectors of diseases, the biology, ethology and ecology of pests and their antagonists, and the use of other beneficial organisms in pest control. The journal covers all noxious or damaging groups of animals, including arthropods, nematodes, molluscs, and vertebrates. Journal of Pest Science devotes special attention to emerging and innovative pest control strategies, including the side effects of such approaches on non-target organisms, for example natural enemies and pollinators, and the implementation of these strategies in integrated pest management. Journal of Pest Science also publishes papers on the management of agro- and forest ecosystems where this is relevant to pest control. Papers on important methodological developments relevant for pest control will be considered as well.
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