Smart bandages for wound monitoring and treatment

IF 10.7 1区 生物学 Q1 BIOPHYSICS
Ping Wu , Long Jin , Wanying Jiang , Yingzhang Zhou , Lisheng Lin , Hongxin Lin , Hu Chen
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引用次数: 0

Abstract

Wound management plays a crucial role in nursing care as it facilitates effective wound healing and prevents infections. To overcome limitations associated with traditional treatment methods, various smart bandages have been developed. The monitoring of wound parameters and the implementation of targeted treatments are crucial aspects of smart bandage development. Smart bandages, as cutting-edge flexible wearable medical devices, integrate various sensing technologies, providing new insights for dynamic monitoring and personalized treatment of chronic wounds. This paper systematically summarizes the applications and developments of smart bandages in monitoring wound environmental parameters, focusing on two major detection methods: colorimetric sensing and electrochemical sensing. Colorimetric sensors typically rely on color changes induced by physiological parameters, which can not only be identified by the naked eye but also combined with image recognition algorithms for physiological parameter detection. Electrochemical sensors, on the other hand, modify electrodes with specific enzymes and detect physiological parameters through the electrical signals generated by redox reactions. In addition to sensing, this paper further explores the integrated application of three smart therapeutic strategies in smart bandages, including promoting cell proliferation and angiogenesis through electrical stimulation, achieving controlled drug release via responsive materials, and utilizing photothermal materials for efficient antibacterial treatment of wounds. Finally, the paper delves into the challenges these bandages face in system integration and clinical translation, and discusses their potential in personalized wound care.
用于伤口监测和治疗的智能绷带
伤口管理在护理中起着至关重要的作用,因为它有助于有效的伤口愈合和预防感染。为了克服传统治疗方法的局限性,各种智能绷带已经被开发出来。伤口参数的监测和靶向治疗的实施是智能绷带发展的关键方面。智能绷带作为一种尖端的柔性可穿戴医疗设备,集成了多种传感技术,为慢性伤口的动态监测和个性化治疗提供了新的见解。本文系统总结了智能绷带在伤口环境参数监测中的应用和发展,重点介绍了两种主要的检测方法:比色传感和电化学传感。比色传感器通常依靠生理参数引起的颜色变化,不仅可以通过肉眼识别,还可以结合图像识别算法进行生理参数检测。另一方面,电化学传感器用特定的酶修饰电极,通过氧化还原反应产生的电信号检测生理参数。除传感外,本文进一步探讨了三种智能治疗策略在智能绷带中的综合应用,包括通过电刺激促进细胞增殖和血管生成,通过反应性材料实现药物可控释放,以及利用光热材料对伤口进行高效抗菌治疗。最后,本文深入探讨了这些绷带在系统集成和临床翻译中面临的挑战,并讨论了它们在个性化伤口护理中的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biosensors and Bioelectronics
Biosensors and Bioelectronics 工程技术-电化学
CiteScore
20.80
自引率
7.10%
发文量
1006
审稿时长
29 days
期刊介绍: Biosensors & Bioelectronics, along with its open access companion journal Biosensors & Bioelectronics: X, is the leading international publication in the field of biosensors and bioelectronics. It covers research, design, development, and application of biosensors, which are analytical devices incorporating biological materials with physicochemical transducers. These devices, including sensors, DNA chips, electronic noses, and lab-on-a-chip, produce digital signals proportional to specific analytes. Examples include immunosensors and enzyme-based biosensors, applied in various fields such as medicine, environmental monitoring, and food industry. The journal also focuses on molecular and supramolecular structures for enhancing device performance.
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