Chirag Mehta , Abraham Shin , Brian Osorio , Daniel DePolo , Irene Vargas , Emily Hao , Ali Khan , Sahas Chandragiri , Sandipan Shringi , Paige O. McLean Diaz , Nicholas S. Potter , Mark Godding , Athena Poppas , Rachna Kataria , Marwan Saad , Omar Hyder , Neel R. Sodha , J. Dawn Abbott , Saraschandra Vallabhajosyula
{"title":"Management of non-Cardiac Organ Failure in cardiogenic shock","authors":"Chirag Mehta , Abraham Shin , Brian Osorio , Daniel DePolo , Irene Vargas , Emily Hao , Ali Khan , Sahas Chandragiri , Sandipan Shringi , Paige O. McLean Diaz , Nicholas S. Potter , Mark Godding , Athena Poppas , Rachna Kataria , Marwan Saad , Omar Hyder , Neel R. Sodha , J. Dawn Abbott , Saraschandra Vallabhajosyula","doi":"10.1016/j.ahjo.2025.100549","DOIUrl":null,"url":null,"abstract":"<div><div>Cardiogenic shock (CS) is a syndrome of low cardiac output leading to systemic hypoperfusion. The mainstay of management involves optimizing preload, afterload, and contractility to restore central hemodynamics. However, CS is frequently complicated by non-cardiac organ failure, for which there is limited guidance. Herein, we review the pathophysiology, assessment, and management of respiratory, renal, hepatic, and neurological failure in the context of CS. This review is intended to provide an evidence-based framework for the management of extracardiac sequelae for the patients in the cardiac and medical intensive care unit.</div></div>","PeriodicalId":72158,"journal":{"name":"American heart journal plus : cardiology research and practice","volume":"55 ","pages":"Article 100549"},"PeriodicalIF":1.3000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American heart journal plus : cardiology research and practice","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666602225000527","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Cardiogenic shock (CS) is a syndrome of low cardiac output leading to systemic hypoperfusion. The mainstay of management involves optimizing preload, afterload, and contractility to restore central hemodynamics. However, CS is frequently complicated by non-cardiac organ failure, for which there is limited guidance. Herein, we review the pathophysiology, assessment, and management of respiratory, renal, hepatic, and neurological failure in the context of CS. This review is intended to provide an evidence-based framework for the management of extracardiac sequelae for the patients in the cardiac and medical intensive care unit.