A Regioselective Ruthenium-Catalyzed Oxidative C–H Alkenylation of 2-Aryl-4H-Benzo[d][1,3] Oxazin-4-Ones

IF 3.7 2区化学 Q2 CHEMISTRY, APPLIED

Applied Organometallic Chemistry Pub Date : 2025-05-02 DOI:10.1002/aoc.70163

Sepideh Bahrami Nasab, Seyed Iman Alavioon

引用次数: 0

Abstract

2-Aryl-4H-benzo[d][1,3]oxazin-4-one derivatives can be directly alkenylated with alkyl acrylates using a facile Ru (II)-catalyzed process; using Cu (OAc)₂•H₂O as an oxidizer through formation of a pentagon cyclic complex of imine-Ru (II) for C–H activation is described. The unique catalytic reaction is well matched with miscellaneous olefins such as vinyl ketones, acrylonitrile, and acrylates. The aryl rings bearing electronically diverse substituents tolerated the reaction conditions to provide ortho-alkenylation products in high regioselectivities and admissible yields.

查看原文本刊更多论文

钌催化2-芳基- 4h -苯并[d][1,3]恶辛-4-酮的C-H氧化烯化反应

2-芳基- 4h -苯并[d][1,3]恶嗪-4- 1衍生物可通过Ru （II）催化反应与烷基丙烯酸酯直接烯化；描述了用Cu (OAc)2•H2O作为氧化剂，通过形成亚胺- ru （II）的五边形环配合物来活化C-H。该独特的催化反应与乙烯酮、丙烯腈、丙烯酸酯等杂烯烃相匹配。具有不同电子取代基的芳基环耐受反应条件，以高区域选择性和可接受的产率提供邻烯烃化产物。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Applied Organometallic Chemistry 化学-无机化学与核化学

CiteScore

7.80

自引率

10.30%

发文量

408

审稿时长

2.2 months

期刊介绍： All new compounds should be satisfactorily identified and proof of their structure given according to generally accepted standards. Structural reports, such as papers exclusively dealing with synthesis and characterization, analytical techniques, or X-ray diffraction studies of metal-organic or organometallic compounds will not be considered. The editors reserve the right to refuse without peer review any manuscript that does not comply with the aims and scope of the journal. Applied Organometallic Chemistry publishes Full Papers, Reviews, Mini Reviews and Communications of scientific research in all areas of organometallic and metal-organic chemistry involving main group metals, transition metals, lanthanides and actinides. All contributions should contain an explicit application of novel compounds, for instance in materials science, nano science, catalysis, chemical vapour deposition, metal-mediated organic synthesis, polymers, bio-organometallics, metallo-therapy, metallo-diagnostics and medicine. Reviews of books covering aspects of the fields of focus are also published.