Risk factors for failure in short segment pedicle instrumentation in thoracolumbar fractures

IF 1.9 Q3 CLINICAL NEUROLOGY
Ana Vilela , Bibiana Couto , David Ferreira , António Cruz , Joana Azevedo , João Pereira , André Santos-Moreira , Nuno Oliveira , Paulo Gil Ribeiro , Pedro Varanda , Direito-Santos Bruno
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Abstract

Introduction

The management of thoracolumbar fractures, particularly through short-segment posterior fixation (SSPF), remains a topic of ongoing debate in spine surgery.

Research question

This study aimed to identify the factors influencing SSPF failure in traumatic thoracolumbar fractures’ treatment, focusing on variables such as age, bone mineral density (BMD), fracture level, posterior ligamentous complex (PLC) injury, screw length, type of screw (monoaxial or polyaxial), instrumentation of the fractured vertebra and sagittal screw angle (SSA).

Material and methods

A total of 66 patients were included, with 43 in the non-failure group (Group N) and 23 in the failure group (Group F). Failure was defined by criteria including screw pull-out, material failure, loss of vertebral height ≥50%, or postoperative kyphosis ≥30°.

Results

The results indicated that age, the use of monoaxial screws and BMD were statistically significant predictors of failure, with older patients (>60 years) showing an eighteen-fold higher risk of failure. Survival analysis revealed that older patients, those with PLC injuries, and those with monoaxial screw instrumentation experienced failure at significantly earlier times.

Discussion and conclusion

These findings suggest that rigorous patient selection, considering factors such as age, BMD, and screw type, is crucial for minimizing the risk of failure in SSPF treatment. Further multicenter prospective studies with larger sample sizes are necessary to validate these results and enhance risk prediction models.
胸腰椎骨折短节段椎弓根内固定失败的危险因素
胸腰椎骨折的治疗,特别是通过短节段后路固定(SSPF),仍然是脊柱外科中一个持续争论的话题。本研究旨在探讨影响SSPF在创伤性胸腰椎骨折治疗中失效的因素,主要包括年龄、骨密度(BMD)、骨折水平、后韧带复合体(PLC)损伤、螺钉长度、螺钉类型(单轴或多轴)、骨折椎体内固定和矢状螺钉角度(SSA)等。材料与方法共纳入66例患者,其中非失败组43例(N组),失败组23例(F组)。失败的定义标准包括螺钉拔出、材料失效、椎体高度损失≥50%或术后后凸≥30°。结果结果表明,年龄、单轴螺钉的使用和骨密度是失败的有统计学意义的预测因素,年龄较大的患者(60岁)失败的风险高出18倍。生存分析显示,老年患者、PLC损伤患者和单轴螺钉内固定患者在更早的时间内发生失败。讨论和结论这些发现表明,严格的患者选择,考虑年龄、骨密度和螺钉类型等因素,对于最小化SSPF治疗失败的风险至关重要。进一步的多中心前瞻性研究需要更大的样本量来验证这些结果并增强风险预测模型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Brain & spine
Brain & spine Surgery
CiteScore
1.10
自引率
0.00%
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审稿时长
71 days
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