Management of ST-segment elevation acute coronary syndromes in the emergency department of Gabes

IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health Pub Date : 2025-05-01 DOI:10.1016/j.cegh.2025.102005

Samet Amal , Rahma Kallel , Hichem Denguir , Imene Rejeb

{"title":"Management of ST-segment elevation acute coronary syndromes in the emergency department of Gabes","authors":"Samet Amal , Rahma Kallel , Hichem Denguir , Imene Rejeb","doi":"10.1016/j.cegh.2025.102005","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>Acute coronary syndromes (ACS) are one of the leading causes of morbidity and mortality in Tunisia. Timely and effective management in the emergency department is crucial to improving patient outcomes, particularly in cases of ST-segment elevation myocardial infarction (STEMI).</div></div><div><h3>Objective</h3><div>To study the prognosis and management of acute coronary syndromes in the emergency department.</div></div><div><h3>Methods</h3><div>A retrospective, monocentric, cross-sectional, descriptive, and analytical study was conducted at the critical emergency unit of Mohamed Ben Sassi University Hospital in Gabes. The study covered a period from January 1, 2020, to December 31, 2022, lasting 36 months.</div></div><div><h3>Results</h3><div>The mean age of patients was 65.2 ± 13.52 years, with a male-to-female ratio of 3.08. Forty-eight percent of patients were from Gabes city. In 80 % of cases (n = 269), at least one comorbidity was observed, including diabetes (152 patients), hypertension (124 patients), and coronary artery disease (28 patients). Chest pain was the most common symptom, noted in 95.3 % of cases (n = 323). Only 33 patients (9.73 %) had first medical contact within 1 h. Antithrombotic therapy was administered to 97.34 % of patients, and morphine was used in 18 % of cases. Thrombolysis was performed in 36.3 % of cases, with a success rate of 82.9 %. Angioplasty was performed in 10.02 % of cases. Of the patients, 90.26 % were transferred to a coronary care unit (CCU), while 3.53 % were transferred to intensive care, and 6.19 % died.</div></div><div><h3>Conclusion</h3><div>Predictive factors for thrombolysis failure in the acute phase of STEMI are critical for improving emergency management strategies.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":"33 ","pages":"Article 102005"},"PeriodicalIF":1.7000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Epidemiology and Global Health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2213398425000946","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction

Acute coronary syndromes (ACS) are one of the leading causes of morbidity and mortality in Tunisia. Timely and effective management in the emergency department is crucial to improving patient outcomes, particularly in cases of ST-segment elevation myocardial infarction (STEMI).

Objective

To study the prognosis and management of acute coronary syndromes in the emergency department.

Methods

A retrospective, monocentric, cross-sectional, descriptive, and analytical study was conducted at the critical emergency unit of Mohamed Ben Sassi University Hospital in Gabes. The study covered a period from January 1, 2020, to December 31, 2022, lasting 36 months.

Results

The mean age of patients was 65.2 ± 13.52 years, with a male-to-female ratio of 3.08. Forty-eight percent of patients were from Gabes city. In 80 % of cases (n = 269), at least one comorbidity was observed, including diabetes (152 patients), hypertension (124 patients), and coronary artery disease (28 patients). Chest pain was the most common symptom, noted in 95.3 % of cases (n = 323). Only 33 patients (9.73 %) had first medical contact within 1 h. Antithrombotic therapy was administered to 97.34 % of patients, and morphine was used in 18 % of cases. Thrombolysis was performed in 36.3 % of cases, with a success rate of 82.9 %. Angioplasty was performed in 10.02 % of cases. Of the patients, 90.26 % were transferred to a coronary care unit (CCU), while 3.53 % were transferred to intensive care, and 6.19 % died.

Conclusion

Predictive factors for thrombolysis failure in the acute phase of STEMI are critical for improving emergency management strategies.

查看原文本刊更多论文

急诊科st段抬高急性冠状动脉综合征的处理

急性冠脉综合征（ACS）是突尼斯发病率和死亡率的主要原因之一。及时有效的急诊管理对于改善患者预后至关重要，尤其是st段抬高型心肌梗死（STEMI）。目的探讨急诊急性冠状动脉综合征的预后及处理。方法回顾性、单中心、横断面、描述性和分析性研究在加贝斯Mohamed Ben Sassi大学医院急诊科进行。研究时间为2020年1月1日至2022年12月31日，共36个月。结果患者平均年龄65.2±13.52岁，男女性别比3.08。48%的患者来自加贝斯市。在80%的病例（n = 269）中，至少观察到一种合并症，包括糖尿病（152例）、高血压（124例）和冠状动脉疾病（28例）。胸痛是最常见的症状，95.3%的病例（n = 323）出现胸痛。只有33例（9.73%）患者在1小时内进行了首次医疗接触。97.34%的患者接受了抗栓治疗，18%的患者使用了吗啡。溶栓率为36.3%，成功率为82.9%。10.02%的病例行血管成形术。90.26%的患者转入冠心病监护室（CCU）， 3.53%的患者转入重症监护，6.19%的患者死亡。结论STEMI急性期溶栓失败的预测因素对提高应急管理策略至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.60

自引率

7.70%

发文量

218

审稿时长

66 days

期刊介绍： Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.