Design method of porous scaffold based on TPMS and KM growth function

IF 2.5 4区计算机科学 Q2 COMPUTER SCIENCE, SOFTWARE ENGINEERING

Graphical Models Pub Date : 2025-05-02 DOI:10.1016/j.gmod.2025.101265

Yi Zhang, Jiong Liu, Quan Qi

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Abstract

Additive manufacturing technology, as a cutting-edge manufacturing process, has shown great potential in the preparation of 3D tissue engineering scaffolds with complex pore structures. The multi-functional scaffolds produced by this technology can provide a combination of excellent mechanical and biological properties, such as high stiffness, strength, toughness and good fluid permeability. Among many stent design methods, pore shape design based on triply periodic minimal surface is favored because of its advantages in controlling design parameters such as aperture, pore shape and internal channel connectivity. In this paper, a new design method for multi-shape scaffolds is proposed, which combines KM growth function and shape conformal mixing technique to construct a complex pore structure consisting of multiple triply periodic minimal surfaces and arbitrary transition boundaries in a scaffold. The advantage of this method is that it can flexibly control the mixed form of the resulting scaffold, and then explore and optimize a variety of transition pore forms to achieve a combination of multi-functiona characteristics such as high strength and excellent fluid permeability.

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基于TPMS和KM生长函数的多孔支架设计方法

增材制造技术作为一种前沿制造工艺，在制备具有复杂孔隙结构的三维组织工程支架方面显示出巨大的潜力。该技术生产的多功能支架具有较高的刚度、强度、韧性和良好的透气性等优良的机械性能和生物性能。在众多支架设计方法中，基于三周期最小表面的孔形设计因其在孔径、孔形和内部通道连通性等设计参数控制方面的优势而受到青睐。本文提出了一种新的多形状支架设计方法，该方法将KM生长函数与形状保形混合技术相结合，在支架中构建由多个三周期极小面和任意过渡边界组成的复杂孔隙结构。该方法的优点是可以灵活控制所得支架的混合形态，进而探索和优化多种过渡孔隙形态，实现高强度和优异的流体渗透性等多功能特性的结合。

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来源期刊

Graphical Models 工程技术-计算机：软件工程

CiteScore

3.60

自引率

5.90%

发文量

审稿时长

47 days

期刊介绍： Graphical Models is recognized internationally as a highly rated, top tier journal and is focused on the creation, geometric processing, animation, and visualization of graphical models and on their applications in engineering, science, culture, and entertainment. GMOD provides its readers with thoroughly reviewed and carefully selected papers that disseminate exciting innovations, that teach rigorous theoretical foundations, that propose robust and efficient solutions, or that describe ambitious systems or applications in a variety of topics. We invite papers in five categories: research (contributions of novel theoretical or practical approaches or solutions), survey (opinionated views of the state-of-the-art and challenges in a specific topic), system (the architecture and implementation details of an innovative architecture for a complete system that supports model/animation design, acquisition, analysis, visualization?), application (description of a novel application of know techniques and evaluation of its impact), or lecture (an elegant and inspiring perspective on previously published results that clarifies them and teaches them in a new way). GMOD offers its authors an accelerated review, feedback from experts in the field, immediate online publication of accepted papers, no restriction on color and length (when justified by the content) in the online version, and a broad promotion of published papers. A prestigious group of editors selected from among the premier international researchers in their fields oversees the review process.