Sarah Anne J. Guagliardo, Stacey Martin, Carolyn V. Gould, Rebekah Sutter, Daniel Jacobs, Kevin O’Laughlin, Ralph Huits, Concetta Castilletti, J. Erin Staples
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引用次数: 0
Abstract
Determining the incubation period of Oropouche virus disease can inform clinical and public health practice. We analyzed data from 97 travel-associated cases identified by the Centers for Disease Control and Prevention (n = 74) or the GeoSentinel Network (n = 13) and 10 cases from published literature. Using log-normal interval-censored survival analysis, we estimated the median incubation period to be 3.2 (95% CI 2.5–3.9) days. Symptoms developed by 1.1 (95% CI 0.6–1.5) days for 5% of patients, 9.7 (95% CI 6.9–12.5) days for 95% of patients, and 15.4 (95% CI 9.6–21.3) days for 99% of patients. The estimated incubation period range of 1–10 days can be used to assess timing and potential source of exposure in patients with Oropouche symptoms. For patients with symptom onset >2 weeks after travel, clinicians and public health responders should consider the possibility of local vectorborne transmission or alternative modes of transmission.
确定Oropouche病毒病的潜伏期可为临床和公共卫生实践提供信息。我们分析了疾病控制和预防中心（n = 74）或地理哨兵网络（n = 13）确定的97例旅行相关病例和10例已发表文献的数据。使用对数正态间隔剔除生存分析，我们估计中位潜伏期为3.2天（95% CI 2.5-3.9）。5%的患者出现症状的时间为1.1 （95% CI 0.6-1.5）天，95%的患者为9.7 （95% CI 6.9-12.5）天，99%的患者为15.4 （95% CI 9.6-21.3）天。估计潜伏期范围为1-10天，可用于评估出现Oropouche症状的患者的时间和潜在接触源。对于在旅行后2周出现症状的患者，临床医生和公共卫生应对人员应考虑本地媒介传播或其他传播方式的可能性。
期刊介绍：
Emerging Infectious Diseases is a monthly open access journal published by the Centers for Disease Control and Prevention. The primary goal of this peer-reviewed journal is to advance the global recognition of both new and reemerging infectious diseases, while also enhancing our understanding of the underlying factors that contribute to disease emergence, prevention, and elimination.
Targeted towards professionals in the field of infectious diseases and related sciences, the journal encourages diverse contributions from experts in academic research, industry, clinical practice, public health, as well as specialists in economics, social sciences, and other relevant disciplines. By fostering a collaborative approach, Emerging Infectious Diseases aims to facilitate interdisciplinary dialogue and address the multifaceted challenges posed by infectious diseases.
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