Avian Influenza A(H5N1) Isolated from Dairy Farm Worker, Michigan

IF 7.2 2区医学 Q1 IMMUNOLOGY

Emerging Infectious Diseases Pub Date : 2025-05-02 DOI:10.3201/eid3106.250386

Nicole Brock, Joanna A. Pulit-Penaloza, Jessica A. Belser, Claudia Pappas, Xiangjie Sun, Troy J. Kieran, Hui Zeng, Juan A. De La Cruz, Yasuko Hatta, Han Di, C. Todd Davis, Terrence M. Tumpey, Taronna R. Maines

引用次数: 0

Abstract

Influenza A(H5N1) viruses have been detected in US dairy cow herds since 2024. We assessed the pathogenesis, transmission, and airborne release of A/Michigan/90/2024, an H5N1 isolate from a dairy farm worker in Michigan, in the ferret model. Results show this virus caused airborne transmission with moderate pathogenicity, including limited extrapulmonary spread, without lethality.

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从密歇根州奶牛场工人分离出禽流感A（H5N1）

自2024年以来，在美国奶牛群中发现了甲型H5N1流感病毒。我们在雪貂模型中评估了来自密歇根州一名奶牛场工人的H5N1分离物A/Michigan/90/2024的发病机制、传播和空气传播。结果表明，该病毒可引起空气传播，致病性中等，包括有限的肺外传播，无致命性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Emerging Infectious Diseases 医学-传染病学

CiteScore

17.30

自引率

1.70%

发文量

505

审稿时长

1 months

期刊介绍： Emerging Infectious Diseases is a monthly open access journal published by the Centers for Disease Control and Prevention. The primary goal of this peer-reviewed journal is to advance the global recognition of both new and reemerging infectious diseases, while also enhancing our understanding of the underlying factors that contribute to disease emergence, prevention, and elimination. Targeted towards professionals in the field of infectious diseases and related sciences, the journal encourages diverse contributions from experts in academic research, industry, clinical practice, public health, as well as specialists in economics, social sciences, and other relevant disciplines. By fostering a collaborative approach, Emerging Infectious Diseases aims to facilitate interdisciplinary dialogue and address the multifaceted challenges posed by infectious diseases.