Intimate partner violence and cognitive functioning – toward quantifying dementia risk

IF 13 1区医学 Q1 CLINICAL NEUROLOGY

Alzheimer's & Dementia Pub Date : 2025-05-02 DOI:10.1002/alz.70029

Audrey R. Murchland, Sebastien Haneuse, Rebecca B. Lawn, Lisa Berkman, Karen Jakubowski, M. Maria Glymour, Karestan C. Koenen

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引用次数: 0

Abstract

INTRODUCTION

Intimate partner violence (IPV) victimization is highly common among women and associated with adverse health consequences that may be linked to dementia risk.

METHODS

Nurses’ Health Study II participants (N = 14,771) reported adult (age ≥ 18) emotional, physical, and sexual IPV in 2001/2008 and completed the Cogstate Brief Battery 2014–2019 (4/6 maximum assessments). Any versus no IPV and IPV subtypes were used to predict cognition in confounder-adjusted generalized estimating equation models weighted to account for attrition.

RESULTS

Mean age at baseline was 61.0 years (standard deviation = 4.6); 46.5% reported any IPV (42.3% emotional, 22.6% physical, and 11.3% sexual). IPV victimization was associated with 0.029 SD unit (95% confidence interval [CI]: −0.068, 0.009) lower global cognitive score but not rate of cognitive change. Among IPV types, emotional IPV had the strongest association (β = −0.048; 95% CI: −0.075, −0.020) with cognitive scores.

DISCUSSION

Gendered social experiences such as IPV may influence dementia risk. Further assessment of IPV in aging cohorts is needed.

Highlights

IPV predicted lower average cognitive score over follow-up.
Emotional abuse had the largest associations with cognitive score among subtypes.
We found no differences in rate of cognitive score change by violence exposure.
Even modest impacts of violence would translate to large population effects.
Gendered experiences warrant additional research in understanding dementia risk.

Abstract Image

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亲密伴侣暴力和认知功能——迈向量化痴呆风险

亲密伴侣暴力（IPV）受害在妇女中非常普遍，并与可能与痴呆风险相关的不利健康后果有关。方法护士健康研究II参与者（N = 14,771）在2001/2008年报告了成人（年龄≥18岁）的情绪、身体和性IPV，并完成了Cogstate Brief Battery 2014-2019（4/6最大评估）。任何或没有IPV和IPV亚型被用来预测混杂因素调整后的广义估计方程模型的认知，加权考虑了损耗。结果基线时平均年龄为61.0岁（标准差= 4.6）；46.5%的人报告有IPV（42.3%情绪上的，22.6%身体上的，11.3%性方面的）。IPV受害与0.029 SD单位（95%可信区间[CI]:−0.068,0.009）的整体认知评分降低相关，但与认知改变率无关。在IPV类型中，情绪性IPV的相关性最强(β =−0.048；95% CI:−0.075,−0.020)。性别社会经历如IPV可能影响痴呆风险。需要进一步评估老年人群的IPV。IPV预测随访期间平均认知评分较低。在各亚型中，情感虐待与认知得分的关联最大。我们发现暴力暴露对认知评分的变化率没有影响。即使是轻微的暴力影响也会转化为大规模的人口影响。性别经验需要进一步的研究来了解痴呆症的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Alzheimer's & Dementia 医学-临床神经学

CiteScore

14.50

自引率

5.00%

发文量

299

审稿时长

3 months

期刊介绍： Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.