Harmonized cognitive performance in an older adult cohort of Vietnamese American immigrants: The VIP study

IF 13 1区医学 Q1 CLINICAL NEUROLOGY

Alzheimer's & Dementia Pub Date : 2025-05-02 DOI:10.1002/alz.70097

Brandon E. Gavett, Sarah Tomaszewski Farias, Quyen Q. Tiet, Van T. Park, Danielle Harvey, Quyen Vuong, Ladson Hinton, Alka M. Kanaya, Rachel A. Whitmer, Lauren Mai, Oanh L. Meyer

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Abstract

INTRODUCTION

Vietnamese Americans represent an understudied population with unique risk factors relevant to cognitive aging. The current study sought to model global cognition in the Vietnamese Insights into Cognitive Aging Program (VIP) study and harmonize ability estimates with the National Alzheimer's Coordinating Center (NACC) Uniform Data Set.

METHODS

Cognitive data from VIP (N = 548) and NACC (N = 15,923) were analyzed using item response theory. Seven common items were assessed for differential item functioning (DIF); items without salient DIF were used to harmonize the cognitive composite score across the two cohorts.

RESULTS

Although five of the seven common items showed evidence of DIF, the magnitude of this DIF was negligible, affecting the factor score estimates of only 12 (2.19%) VIP participants by more than one standard error.

DISCUSSION

Global cognitive functioning can be estimated in Vietnamese American immigrants with minimal bias and psychometrically matched to one of the largest studies of cognitive aging and dementia worldwide.

Highlights

This is the first known study to model cognition in older Vietnamese Americans.
Global cognition was harmonized with minimal bias across two diverse cohorts.
Differential item functioning was found in five of seven items, but the impact was not salient.
Results create new opportunities to study health disparities in an underrepresented group.

Abstract Image

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越南裔美国移民老年人群体的协调认知表现：VIP研究

越南裔美国人是一个未被充分研究的人群，具有与认知衰老相关的独特危险因素。目前的研究试图在越南认知衰老计划（VIP）研究中建立全球认知模型，并与国家阿尔茨海默病协调中心（NACC）统一数据集协调能力估计。方法采用项目反应理论对VIP （N = 548）和NACC （N = 15923）的认知数据进行分析。评估了七个常见项目的差异项目功能（DIF）；使用无显著DIF的项目来协调两个队列的认知综合得分。结果：虽然7个常见项目中有5个显示了DIF的证据，但该DIF的大小可以忽略不计，仅影响12名VIP参与者（2.19%）的因子评分估计值超过一个标准误差。越南裔美国移民的全球认知功能可以以最小的偏差进行估计，并且心理测量学上与全球最大的认知衰老和痴呆研究之一相匹配。这是已知的第一个对老年越南裔美国人的认知建模的研究。在两个不同的队列中，全球认知以最小的偏差协调一致。在7个项目中，有5个项目的功能存在差异，但影响并不显著。结果为研究代表性不足的群体的健康差异创造了新的机会。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Alzheimer's & Dementia 医学-临床神经学

CiteScore

14.50

自引率

5.00%

发文量

299

审稿时长

3 months

期刊介绍： Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.