Effects of aerobic exercise on memory functions and serum levels of BDNF and TrkB in young adult and older adult male football players

IF 2.4 2区医学 Q2 SPORT SCIENCES

Journal of Exercise Science & Fitness Pub Date : 2025-04-16 DOI:10.1016/j.jesf.2025.100385

Naseh Jahani , Vahid Valipour Dehnou , Rasoul Eslami , Daniel Gahreman

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引用次数: 0

Abstract

Background/Objective

This study aimed to investigate the effect of aerobic exercise on verbal memory (VM) and non-verbal memory (NVM) functions as well as BDNF and TrkB serum levels in young and older adult male football players.

Methods

Twenty-nine male football players voluntarily participated in this study and were divided into two age groups: G1 (young; 19–30 years old, n = 15, football experience 10.6 ± 2.79 years) and G2 (older; 46–71 years old, n = 14, football experience 35.78 ± 9.48 years). Serum BDNF and TrkB levels and performance on the VM and NVM tests were measured before and after a 60-min aerobic exercise session. A 2 (Time) x 2 (Group) mixed-model repeated measures ANOVA test was used to detect the effects of exercise and age differences.

Results

There was a statistically significant time × group interaction of age and exercise on BDNF and TrkB levels (p < 0.01, p < 0.001; respectively). However, this interaction was not observed for VM and NVM (p = 0.751, p = 0.869; respectively). There was also a significant effect of the group on BDNF, TrkB, and NVM (p < 0.001, p < 0.001, p < 0.01; respectively), whereas there was not a significant effect on VM (p = 0.094). Furthermore, there was a significant effect of time on BDNF, TrkB, and VM (p < 0.001, for all); but not on NVM (p = 0.110).

Conclusion

Regular football training participation can maintain BDNF levels as a neurotrophin that can improve cognitive functions. Likewise, this neurotrophin and its receptor's response to aerobic exercise in old age suggests the effectiveness of exercise as a preventive strategy against age-related memory loss and neurodegeneration.

查看原文本刊更多论文

有氧运动对青年和老年男性足球运动员记忆功能及血清BDNF和TrkB水平的影响

背景/目的探讨有氧运动对青年和老年成年男子足球运动员言语记忆（VM）和非言语记忆（NVM）功能及血清BDNF和TrkB水平的影响。方法29名男性足球运动员自愿参加本研究，并将其分为两个年龄组：G1(年轻；19-30岁，n = 15，足球经历10.6±2.79年),G2(年龄较大；46-71岁，n = 14，足球经验35.78±9.48年)。在60分钟有氧运动之前和之后测量血清BDNF和TrkB水平以及VM和NVM测试的表现。采用2（时间）× 2（组）混合模型重复测量方差分析检验运动和年龄差异的影响。结果年龄和运动对BDNF和TrkB水平的时间×组交互作用有统计学意义(p <；0.01, p <；0.001;分别)。然而，VM和NVM没有观察到这种相互作用(p = 0.751, p = 0.869；分别)。该组对BDNF、TrkB和NVM也有显著影响(p <；0.001, p <；0.001, p <；0.01;对VM无显著影响（p = 0.094）。此外，时间对BDNF、TrkB和VM有显著影响(p <；0.001，所有)；但在NVM上没有（p = 0.110）。结论定期参加足球训练可维持BDNF水平，作为一种神经营养因子，可改善认知功能。同样，这种神经营养因子及其受体对老年有氧运动的反应表明，运动作为一种预防与年龄相关的记忆丧失和神经变性的有效策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Exercise Science & Fitness 医学-运动科学

CiteScore

5.10

自引率

3.60%

发文量

审稿时长

31 days

期刊介绍： The Journal of Exercise Science and Fitness is the official peer-reviewed journal of The Society of Chinese Scholars on Exercise Physiology and Fitness (SCSEPF), the Physical Fitness Association of Hong Kong, China (HKPFA), and the Hong Kong Association of Sports Medicine and Sports Science (HKASMSS). It is published twice a year, in June and December, by Elsevier. The Journal accepts original investigations, comprehensive reviews, case studies and short communications on current topics in exercise science, physical fitness and physical education.