Insights into the evolution and genetic diversity of the Malus genus from pan-genome analysis

IF 31.7 1区生物学 Q1 GENETICS & HEREDITY

Nature genetics Pub Date : 2025-04-29 DOI:10.1038/s41588-025-02171-9

引用次数: 0

Abstract

We provide an in-depth pan-genome analysis of 30 Malus species, revealing potential mechanisms of ancient gene duplications, introgressions and polyploidization that drive genetic diversity and adaptability. Furthermore, we shed light on apple domestication, identify markers for disease resistance and present new strategies for uncovering genes with breeding potential.

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从泛基因组分析了解苹果属的进化和遗传多样性

我们对30个苹果物种进行了深入的泛基因组分析，揭示了古代基因复制、基因渗入和多倍体化驱动遗传多样性和适应性的潜在机制。此外，我们还揭示了苹果的驯化、抗病标记的鉴定以及发现具有育种潜力的基因的新策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature genetics 生物-遗传学

CiteScore

43.00

自引率

2.60%

发文量

241

审稿时长

3 months

期刊介绍： Nature Genetics publishes the very highest quality research in genetics. It encompasses genetic and functional genomic studies on human and plant traits and on other model organisms. Current emphasis is on the genetic basis for common and complex diseases and on the functional mechanism, architecture and evolution of gene networks, studied by experimental perturbation. Integrative genetic topics comprise, but are not limited to: -Genes in the pathology of human disease -Molecular analysis of simple and complex genetic traits -Cancer genetics -Agricultural genomics -Developmental genetics -Regulatory variation in gene expression -Strategies and technologies for extracting function from genomic data -Pharmacological genomics -Genome evolution