The emergence of a novel mpox virus strain (clade Ib) in Central Africa: A global public health concern

IF 4.7 3区医学 Q1 INFECTIOUS DISEASES

Journal of Infection and Public Health Pub Date : 2025-04-16 DOI:10.1016/j.jiph.2025.102781

Zahra Labiba Ahmed, Md. Rabiul Islam

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引用次数: 0

Abstract

Monkeypox (mpox) infection gained global attention when it spread outside Africa in 2003. A novel mpox strain was identified in the Central African Republic in 2024. This new variant presents significant clinical and epidemiological differences from previously known strains. The high rate of pediatric infection, shortened incubation period, rapid transmission, unusual symptoms, accelerated disease progression, and higher case fatality rate make this strain a potential public health concern. Current epidemiological data suggest a case fatality rate of approximately 8–10 %, higher than clade II (West African strain). We recommend considering this new mpox strain as a top priority for international healthcare authorities. International health organizations must provide support to nations with fragile healthcare infrastructures. Immediate actions are essential to prevent this emerging variant from escalating into a larger epidemic. Global healthcare organizations should apply lessons learned from previous outbreaks of infectious diseases to mitigate this new threat.

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中非出现一种新型m痘病毒株（进化支Ib）：一个全球公共卫生问题

猴痘感染在2003年传播到非洲以外时引起了全球的关注。2024年在中非共和国发现了一种新的痘病毒株。这种新的变异与以前已知的菌株有显著的临床和流行病学差异。小儿感染率高、潜伏期短、传播迅速、症状异常、疾病进展加速以及较高的病死率使该菌株成为潜在的公共卫生问题。目前的流行病学数据表明，病死率约为8 - 10% %，高于II支（西非毒株）。我们建议将这一新的mpox毒株作为国际卫生保健当局的首要任务加以考虑。国际卫生组织必须向卫生基础设施脆弱的国家提供支持。必须立即采取行动，防止这种新出现的变种升级为更大的流行病。全球卫生保健组织应运用从以往传染病爆发中吸取的经验教训，减轻这一新的威胁。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Infection and Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -INFECTIOUS DISEASES

CiteScore

13.10

自引率

1.50%

发文量

203

审稿时长

96 days

期刊介绍： The Journal of Infection and Public Health, first official journal of the Saudi Arabian Ministry of National Guard Health Affairs, King Saud Bin Abdulaziz University for Health Sciences and the Saudi Association for Public Health, aims to be the foremost scientific, peer-reviewed journal encompassing infection prevention and control, microbiology, infectious diseases, public health and the application of healthcare epidemiology to the evaluation of health outcomes. The point of view of the journal is that infection and public health are closely intertwined and that advances in one area will have positive consequences on the other. The journal will be useful to all health professionals who are partners in the management of patients with communicable diseases, keeping them up to date. The journal is proud to have an international and diverse editorial board that will assist and facilitate the publication of articles that reflect a global view on infection control and public health, as well as emphasizing our focus on supporting the needs of public health practitioners. It is our aim to improve healthcare by reducing risk of infection and related adverse outcomes by critical review, selection, and dissemination of new and relevant information in the field of infection control, public health and infectious diseases in all healthcare settings and the community.