Effects of hearing aids on early prelingual auditory development in children with unilateral cochlear implantation: a linear mixed model for longitudinal data

IF 1.2 4区医学 Q3 OTORHINOLARYNGOLOGY

International journal of pediatric otorhinolaryngology Pub Date : 2025-04-24 DOI:10.1016/j.ijporl.2025.112366

Mei Li , Wei-li Kong , Ning-ying Song

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引用次数: 0

Abstract

Introduction

We conducted a liner mixed model to explore the two-year early prelingual auditory development (EPLAD) of children with and without hearing aids (HAs) after unilateral cochlear implantation (CI) through a longitudinal study.

Methods

86 children with unilateral CI were divided into CI + HA (46) and CI (40) groups. Their EPLAD was assessed using the Infant Toddler Meaningful Auditory Integration Scale (IT/MAIS) before CI and at 1st, 3rd, 6th, 12th, 18th, and 24th months post-activation. A spline function described the EPLAD trajectory, and a best-fitting curve predicted IT/MAIS score changes over time. A linear mixed model analyzed the effects of HAs on EPLAD.

Results

CI + HA group had significantly higher IT/MAIS scores pre-op and up to 18 months post-CI (p < 0.01). There was no significant difference in the trajectory of EPLAD among different sex and age groups (p > 0.05). ITMAIS, sound detection and sound recognition trajectory of CI + HA group was significantly different from that of CI group (p < 0.01). We constructed a predictive score of IT/MAIS, sound detection and sound recognition over time with high accuracy (R = 0.99).

Conclusions

Most of studies about the effects of HAs on auditory development after CI merely conducted cross-sectional approach, which cannot reflect the real changes of individuals. For children with unilateral cochlear implant, wearing hearing aids in the contralateral ear can continuously improve EPLAD. The auditory development of individual is a dynamic process, and longitudinal study is more advantage to explore the real differences.

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助听器对单侧人工耳蜗植入儿童早期语前听觉发育的影响：纵向数据的线性混合模型

本研究采用线性混合模型，通过纵向研究，探讨单侧人工耳蜗植入（CI）后，带助听器和不带助听器（HAs）儿童两年早期语前听觉发育（EPLAD）。方法86例单侧CI患儿分为CI + HA组（46例）和CI组（40例）。在CI前和激活后的第1、3、6、12、18和24个月，使用婴幼儿有意义听觉整合量表（IT/MAIS）评估他们的EPLAD。样条函数描述了EPLAD轨迹，最佳拟合曲线预测了IT/MAIS评分随时间的变化。采用线性混合模型分析了HAs对EPLAD的影响。结果sci + HA组术前及ci后18个月的IT/MAIS评分均显著高于对照组(p <；0.01)。EPLAD的发展轨迹在不同性别和年龄组间无显著差异(p >；0.05)。CI + HA组ITMAIS、声音检测及声音识别轨迹与CI组差异有统计学意义(p <；0.01)。我们构建了IT/MAIS、声音检测和声音识别随时间变化的预测评分，准确率很高（R = 0.99）。结论目前关于ha对CI术后听觉发育影响的研究多采用横断面方法，不能反映个体的真实变化。对于单侧人工耳蜗患儿，在对侧耳佩戴助听器可持续改善EPLAD。个体听觉发展是一个动态的过程，纵向研究更有利于探究个体听觉发展的真实差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International journal of pediatric otorhinolaryngology 医学-耳鼻喉科学

CiteScore

3.20

自引率

6.70%

发文量

276

审稿时长

62 days

期刊介绍： The purpose of the International Journal of Pediatric Otorhinolaryngology is to concentrate and disseminate information concerning prevention, cure and care of otorhinolaryngological disorders in infants and children due to developmental, degenerative, infectious, neoplastic, traumatic, social, psychiatric and economic causes. The Journal provides a medium for clinical and basic contributions in all of the areas of pediatric otorhinolaryngology. This includes medical and surgical otology, bronchoesophagology, laryngology, rhinology, diseases of the head and neck, and disorders of communication, including voice, speech and language disorders.