Theoretical and experimental study of laser irradiation in superficial /deep skin with different absorption temperature characteristics

Abstract

To elucidate the temperature transfer characteristics of biological tissue under continuous laser irradiation, simulations were conducted for two wavelengths, 671 nm, and 1064 nm, to investigate temperature variations and thermal diffusion at different depths within and on the surface of biological tissue under varying power densities and irradiation times. The reliability of the simulations was verified through experimental validation. A finite element-based study was conducted to obtain the spatiotemporal temperature distribution within the skin tissue by solving Pennes' bioheat transfer equation and applying the Beer-Lambert law. The information presented on spatiotemporal temperature distribution and the key factors influencing it will help optimize laser parameters and irradiation doses, enabling safe and effective photothermal effects through continuous laser irradiation.