Correction to “Microfluidic Spinning of Cell-Responsive Grooved Microfibers”

Abstract

Adv. Funct. Mater., 2015, 25, 1404531

DOI: 10.1002/adfm.201404531

Concerns were raised by a third party regarding overlapping image panels within the article (Figure 5A,B). The authors acknowledged the image compilation error, nevertheless, due to the elapsed time since publication, the original data were not available.

The authors have repeated the experiment based on the published methods and compiled a new panel showing the viability of encapsulated C2C12 cells at day 7. The new data confirmed the same trends as observed before, therefore the experimental results and the corresponding conclusions of the paper remain unaffected. The authors apologize for this mistake.

The corrected Figure 5 A,B is below:

Figure 5. Viability of cells encapsulated in 30% GelMA and 4% Alginate microstructured fibers. A,B) Fluorescent images of C2C12 myoblast cells encapsulated at high cell density (12 × 10 6 cells in 1 mL solution) in 30% GelMA and 4% alginate fibers stained with Calcein AM (living cells, green) and ethidium homodimer-1 (dead cells, red) at day 7 of culture.

In addition, the figure caption of Figure 4 has been revised, as follows:

“Cell alignment induced by the grooved/ridged microstructure on GelMA fibers. A,B) Fluorescent images of living cells (green) stained with Calcein AM at day 3 of culture. No dead cells (red) stained with ethidium homodimer-1 were observed. Panel B is a representative image of higher magnification and does not correspond to the exact location marked red in panel A. C,D) Fluorescent images showing cell orientation of F-actin (red) and cell nuclei (blue) stained, respectively, with Alexa Fluor 546-phalloidin and DAPI. E) FE-SEM image showing the cell colonization and alignment along the grooves of the GelMA fiber. F) Cell alignment quantification for cells cultured on 30% GelMA microstructured fibers and 30% GelMA fibers with smooth surfaces. Error bars represent standard error.”