Residential greenspace and lung function throughout childhood and adolescence in five European birth cohorts. A CADSET initiative

IF 10.3 1区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environment International Pub Date : 2025-05-01 DOI:10.1016/j.envint.2025.109493

Carlos A. Valencia-Hernández , Zhebin Yu , Ulrike Gehring , Gerard H. Koppelman , Marie Standl , Claudia Flexeder , Tamara Schikowski , Sara Kress , Erik Melén , Olena Gruzieva , Mare Lõhmus , Rosa Faner , Alvar Agusti , Jadwiga A. Wedzicha , Judith Garcia-Aymerich , Sarah Koch , Mark Nieuwenhuijsen , Aitana Lertxundi , Ana Esplugues , Ferran Ballester , Elaine Fuertes

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Abstract

Whether greenspace affects lung function is unclear. We explored associations between the level of greenness or presence of urban green space near the home with lung function measures taken repeatedly during childhood and adolescence in five European birth cohorts.

Lung function was measured by spirometry between six and 22 years (2–3 times), and 9,206 participants from BAMSE (Sweden), GINI/LISA South and GINI/LISA North (Germany), PIAMA (The Netherlands) and INMA (Spain) contributed at least one lung function measurement. The mean Normalized Difference Vegetation Index (NDVI) in a 300 m buffer and presence of urban green space within a 300 m buffer (yes/no) were estimated at the home address at the time of each spirometry measurement. Cohort-specific associations were assessed using adjusted linear mixed models and combined in a random-effects meta-analysis.

Residential greenness was not associated with forced expiratory volume in one second (FEV₁), forced vital capacity (FVC) or FEV₁/FVC in the meta-analysis (2.3 ml [-3.2, 7.9], 6.2 ml [-3.4, 15.7] and −0.1 [-0.3, 0.1] per 0.1 increase in NDVI, respectively), nor was having a nearby urban green space (−8.6 ml [–22.3, 5.0], −7.6 ml [-24.7, 9.4] and 0.0 [-0.4, 0.3], respectively). Heterogeneity was low to moderate (I² = 0 –39 %). Asthma, atopy, air pollution, sex, socioeconomic status and urbanization did not modify the null associations.

Using repeated data from five large independent European birth cohorts, we did not find associations between vegetation levels around the home or the presence of an urban green space and lung function levels during childhood and adolescence.

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五个欧洲出生队列中的居住绿地与儿童和青少年时期的肺功能。CADSET 计划

绿地是否会影响肺功能尚不清楚。我们在五个欧洲出生队列中探讨了绿化水平或住宅附近是否有城市绿地与儿童和青少年时期反复测量肺功能之间的关系。肺功能在 6 至 22 岁期间通过肺活量测定法进行测量（2-3 次），来自 BAMSE（瑞典）、GINI/LISA South 和 GINI/LISA North（德国）、PIAMA（荷兰）和 INMA（西班牙）的 9206 名参与者至少进行了一次肺功能测量。在每次肺活量测量时，根据家庭住址估算了 300 米缓冲区内的归一化差异植被指数 (NDVI) 平均值和 300 米缓冲区内是否有城市绿地（是/否）。在荟萃分析中，住宅绿化与一秒钟用力呼气容积（FEV1）、用力肺活量（FVC）或 FEV1/FVC 无关（2.3毫升[-3.2，7.9]、6.2毫升[-3.4，15.7]和-0.1[-0.3，0.1]），附近有城市绿地也与之无关（分别为-8.6毫升[-22.3，5.0]、-7.6毫升[-24.7，9.4]和0.0[-0.4，0.3]）。异质性为中低度（I2 = 0 -39%）。哮喘、阿特匹克、空气污染、性别、社会经济地位和城市化并未改变无效关联。

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来源期刊

Environment International 环境科学-环境科学

CiteScore

21.90

自引率

3.40%

发文量

734

审稿时长

2.8 months

期刊介绍： Environmental Health publishes manuscripts focusing on critical aspects of environmental and occupational medicine, including studies in toxicology and epidemiology, to illuminate the human health implications of exposure to environmental hazards. The journal adopts an open-access model and practices open peer review. It caters to scientists and practitioners across all environmental science domains, directly or indirectly impacting human health and well-being. With a commitment to enhancing the prevention of environmentally-related health risks, Environmental Health serves as a public health journal for the community and scientists engaged in matters of public health significance concerning the environment.