Diagnostic Value of Echocardiography in Cats With and Without Ultrasonographic Evidence of Renal Infarction

IF 2.1 2区农林科学 Q1 VETERINARY SCIENCES

Journal of Veterinary Internal Medicine Pub Date : 2025-04-24 DOI:10.1111/jvim.70107

Scott D. Gibson, Bianca N. Lourenço, Metzere Bierlein De la Rosa, Amanda E. Coleman, Chris McLaughlin, Allison Arne, Tonya L. Harris, Christianna Ziccardi, Shelly L. Vaden

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引用次数: 0

Abstract

Background

Revisiting the association between heart disease and renal infarction (RI) in cats is relevant to determine whether those with RI should undergo echocardiographic screening.

Objective

Compare the relative frequency of echocardiographically detectable heart disease and other comorbidities in cats with and without ultrasonographic evidence of RI.

Animals

A total of 826 cats that underwent concurrent abdominal ultrasonography and transthoracic echocardiography and were assigned a cardiac diagnosis.

Methods

Two-center cross-sectional study with a study population recruitment period from January 1, 2011 to June 15, 2021. Demographic, clinical, clinicopathologic, and ultrasonographic data were recorded. Available echocardiographic images were reviewed to assign a standardized cardiac diagnosis. Occult heart disease was defined as structural heart disease without clinical signs of congestive heart failure. Risk factors for RI were evaluated by univariable or multivariable logistic regression.

Results

The relative frequency of structural heart disease in cats with and without RI was 63% (114/181) and 46% (297/645), respectively (adjusted odds ratio [OR] 95% confidence interval [CI], 1.6; 1.2–2.3). Older age (p = 0.03), higher maximum end-diastolic left ventricular wall thickness (p = 0.02), higher systolic blood pressure (p = 0.02), auscultable cardiac abnormalities other than murmur (p = 0.04), and diagnosis of acute kidney injury (p = 0.002), chronic kidney disease (p = 0.005), and occult heart disease (OR [95% CI], 2.4 [1.7–3.4]; p ≤ 0.001) were associated with increased risk of RI. Strength and statistical significance of associations varied by site.

Conclusions and Clinical Importance

Occult heart disease is more frequent in cats with RI, and echocardiographic screening of these cats should be considered.

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超声心动图对有无肾梗死猫的诊断价值

背景：重新审视猫的心脏病和肾梗死（RI）之间的关系，有助于确定那些患有RI的猫是否应该接受超声心动图筛查。目的比较超声心动图可检测到的心脏疾病和其他合并症在有和没有超声图像证据的猫中的相对频率。总共826只猫接受了腹部超声检查和经胸超声心动图检查，并被指定为心脏诊断。方法双中心横断面研究，研究人群招募期为2011年1月1日至2021年6月15日。记录人口统计学、临床、临床病理和超声检查数据。检查可用的超声心动图图像，以确定标准化的心脏诊断。隐匿性心脏病被定义为没有充血性心力衰竭临床症状的结构性心脏病。通过单变量或多变量logistic回归评估RI的危险因素。结果伴有和未伴有RI的猫发生结构性心脏病的相对频率分别为63%（114/181）和46%(297/645)(校正优势比[OR] 95%可信区间[CI]， 1.6；1.2 - -2.3)。年龄较大（p = 0.03），舒张末期最大左室壁厚度较高（p = 0.02），收缩压较高（p = 0.02），除杂音外可听心脏异常（p = 0.04），诊断为急性肾损伤（p = 0.002），慢性肾脏疾病（p = 0.005）和隐匿性心脏病(OR [95% CI], 2.4 [1.7-3.4]；p≤0.001)与RI风险增加相关。关联的强度和统计意义因地点而异。结论及临床意义隐匿性心脏病在RI猫中更为常见，应考虑对这些猫进行超声心动图筛查。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Veterinary Internal Medicine 农林科学-兽医学

CiteScore

4.50

自引率

11.50%

发文量

243

审稿时长

22 weeks

期刊介绍： The mission of the Journal of Veterinary Internal Medicine is to advance veterinary medical knowledge and improve the lives of animals by publication of authoritative scientific articles of animal diseases.