Properties and Applications of Ormosil for Biosensing

IF 2.8 3区材料科学 Q3 CHEMISTRY, PHYSICAL

Silicon Pub Date : 2025-02-27 DOI:10.1007/s12633-025-03256-0

Purnima Justa, Nancy Jaswal, Deeksha Rana, Hemant Kumar, Neha Yadav, Vijay Bahadur, Pramod Kumar

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Abstract

Ormosil, known for its unique attributes such as tuneable porosity, ability to possess a high amount of exposed surface area relative to their volume, and compatibility with living organisms, is promising as a biosensor material. This review covers current advances, methods, and obstacles associated with the use of Ormosil-based biosensors for the recognition of various analytes, including biomolecules, ions, and gases. Synthesis methods specifically tailored to biosensing are discussed, with an emphasis on strategies to brush up the sensitivity, selectivity, and stability of the sensors. It concludes by outlining prospects and challenges, emphasizing the potential of Ormosil-based biosensors in healthcare, environmental monitoring, industrial control processes, drug delivery and food safety. It highlights the need for interdisciplinary collaboration and innovative approaches to overcome current limitations and fully exploit Ormosil's capabilities in biosensor applications.

Graphical Abstract

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Ormosil在生物传感中的性能及应用

Ormosil以其独特的特性而闻名，如可调节的孔隙度，相对于其体积具有大量暴露表面积的能力，以及与生物体的相容性，是一种很有前途的生物传感器材料。本文综述了目前基于ormosil的生物传感器用于识别各种分析物（包括生物分子、离子和气体）的进展、方法和障碍。讨论了专门针对生物传感的合成方法，重点介绍了提高传感器灵敏度、选择性和稳定性的策略。报告最后概述了前景和挑战，强调了基于ormosil的生物传感器在医疗保健、环境监测、工业控制过程、药物输送和食品安全方面的潜力。它强调了跨学科合作和创新方法的必要性，以克服当前的限制，并充分利用Ormosil在生物传感器应用方面的能力。图形抽象

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Silicon CHEMISTRY, PHYSICAL-MATERIALS SCIENCE, MULTIDISCIPLINARY

CiteScore

5.90

自引率

20.60%

发文量

685

审稿时长

>12 weeks

期刊介绍： The journal Silicon is intended to serve all those involved in studying the role of silicon as an enabling element in materials science. There are no restrictions on disciplinary boundaries provided the focus is on silicon-based materials or adds significantly to the understanding of such materials. Accordingly, such contributions are welcome in the areas of inorganic and organic chemistry, physics, biology, engineering, nanoscience, environmental science, electronics and optoelectronics, and modeling and theory. Relevant silicon-based materials include, but are not limited to, semiconductors, polymers, composites, ceramics, glasses, coatings, resins, composites, small molecules, and thin films.