Simulation and Design of a Rodent-Specific Transcranial Magnetic Stimulation Coil Based on the Principle of Temporal Interference

IF 2.1 3区工程技术 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC

IEEE Transactions on Magnetics Pub Date : 2025-02-18 DOI:10.1109/TMAG.2025.3543418

Fushuai Gou;Hongli Yu;Xiaoxi Liu;Pengyi Lu;Boai Du

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引用次数: 0

Abstract

Transcranial magnetic stimulation (TMS) is a noninvasive and painless treatment for psychiatric disorders. The basic mechanisms of TMS are understood primarily from studies of rodents. However, due to the relatively small brain size of rodents, the current commercially available animal coils are poorly focusing, leading to an inability to stimulate specific brain regions. To address the above issues, a magnetic stimulation coil is designed for rodents based on the principle of temporal interference and the relationships between the stimulation effect of temporal interference magnetic stimulation (TI-TMS) and the coil parameters are also explored. The result found that the stimulus intensity, stimulus depth, and focusing of

$\Pi $

-core coils are enhanced by 61.8%, 52.3%, and 32.5% compared with the rTMS miniaturized eight-figure coil. A novel discharge circuit for TI-TMS has been designed in this article and the feasibility is verified by saline experiment. The frequency and amplitude of the circuit can be controlled.

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基于时间干扰原理的鼠类专用经颅磁刺激线圈的仿真与设计

经颅磁刺激（TMS）是一种无创、无痛的精神疾病治疗方法。经颅磁刺激的基本机制主要是通过对啮齿动物的研究来了解的。然而，由于啮齿类动物的大脑体积相对较小，目前市售的动物线圈聚焦性差，导致无法刺激特定的大脑区域。针对上述问题，设计了基于时间干扰原理的啮齿动物磁刺激线圈，并探讨了时间干扰磁刺激（TI-TMS）的刺激效果与线圈参数的关系。结果表明，与rTMS小型化8位数线圈相比，$\Pi $磁芯线圈的刺激强度、刺激深度和聚焦分别提高了61.8%、52.3%和32.5%。本文设计了一种新型的TI-TMS放电电路，并通过生理盐水实验验证了其可行性。电路的频率和幅度是可以控制的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

IEEE Transactions on Magnetics 工程技术-工程：电子与电气

CiteScore

4.00

自引率

14.30%

发文量

565

审稿时长

4.1 months

期刊介绍： Science and technology related to the basic physics and engineering of magnetism, magnetic materials, applied magnetics, magnetic devices, and magnetic data storage. The IEEE Transactions on Magnetics publishes scholarly articles of archival value as well as tutorial expositions and critical reviews of classical subjects and topics of current interest.