The prevalence of suicide ideation, suicide attempt and suicide in borderline personality disorder patients: A systematic review and meta-analysis

IF 4.1 2区医学 Q1 PSYCHIATRY

General hospital psychiatry Pub Date : 2025-04-21 DOI:10.1016/j.genhosppsych.2025.04.005

Mohammadmahdi Lak , Shima Shakiba , Behrooz Dolatshahi , Mohammad Saatchi , Mohammadamin Shahrbaf , Atefeh Jafarpour

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引用次数: 0

Abstract

Background

Borderline personality disorder (BPD) is associated with a high risk of suicidality, including suicide ideation, suicide attempts, and suicide. This meta-analysis aims to determine the lifetime prevalence of these dimensions in patients with BPD and to identify associated factors to inform clinical practice and intervention strategies.

Methods

We searched PubMed, Scopus, Web of Science, and Embase for observational articles (cross-sectional, cohort, longitudinal and case-control) reporting suicide ideation, suicide attempts, and suicide in patients with BPD. Data including age, sex, diagnostic criteria, inpatient/outpatient care, comorbidity, and rates of suicide ideation, suicide attempts, and suicide were extracted. A pooled analysis with a random effects model was performed using STATA.

Results

35 studies including 34,832 patients with BPD were included in the final analysis. The pooled rate of suicidal ideation, suicide attempts, and suicides in patients with BPD was 80 % (95 % CI: 61 %–94 %), 52 % (95 % CI: 47 %–58 %), and 6 % (95 % CI: 4 %–8 %), respectively. The younger age group of BPD patients had a significantly higher lifetime prevalence of suicide ideation, and suicide attempt (p < 0.001). The inpatient group of BPD patients had a significantly higher lifetime prevalence of suicidal attempt (p < 0.001), while the outpatient group had a significantly higher lifetime prevalence of suicide (p = 0.003).

Conclusion

BPD carries a high suicide risk, influenced by factors like age and clinical setting, while the impact of comorbid depression remains unclear. Future research should standardize diagnostics and use longitudinal studies to better understand and mitigate suicide risk in BPD.

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边缘型人格障碍患者自杀意念、自杀企图和自杀的患病率：一项系统综述和荟萃分析

边缘型人格障碍（BPD）与高自杀风险相关，包括自杀意念、自杀企图和自杀。本荟萃分析旨在确定BPD患者这些维度的终生患病率，并确定相关因素，为临床实践和干预策略提供信息。方法：检索PubMed、Scopus、Web of Science和Embase，检索报告BPD患者自杀意念、自杀企图和自杀的观察性文章（横断面、队列、纵向和病例对照）。数据包括年龄、性别、诊断标准、住院/门诊护理、合并症、自杀意念、自杀企图和自杀率。采用STATA进行随机效应模型的合并分析。结果35项研究，34,832例BPD患者纳入最终分析。BPD患者自杀意念、自杀企图和自杀的总发生率分别为80% （95% CI: 61% - 94%）、52% （95% CI: 47% - 58%）和6% （95% CI: 4% - 8%）。年轻年龄组的BPD患者一生中自杀意念和自杀企图的患病率明显较高(p <；0.001)。住院组BPD患者的终生自杀企图发生率显著高于住院组(p <；0.001)，而门诊组的终生自杀率显著高于门诊组（p = 0.003）。结论bpd患者存在较高的自杀风险，受年龄、临床环境等因素的影响，而合并抑郁的影响尚不清楚。未来的研究应该使诊断标准化，并使用纵向研究来更好地了解和降低BPD的自杀风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

General hospital psychiatry 医学-精神病学

CiteScore

9.60

自引率

2.90%

发文量

125

审稿时长

20 days

期刊介绍： General Hospital Psychiatry explores the many linkages among psychiatry, medicine, and primary care. In emphasizing a biopsychosocial approach to illness and health, the journal provides a forum for professionals with clinical, academic, and research interests in psychiatry''s role in the mainstream of medicine.