MotherToBaby and CDC: Partnering to Provide a Rapid and Personalized Response to COVID-19 Vaccine Inquiries During Pregnancy and Lactation

IF 1.6 4区医学 Q4 DEVELOPMENTAL BIOLOGY

Birth Defects Research Pub Date : 2025-04-23 DOI:10.1002/bdr2.2477

Kirstie Perrotta, Lorrie Harris-Sagaribay, Gretchen Bandoli

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引用次数: 0

Abstract

Background

When coronavirus disease 2019 (COVID-19) vaccines first became available, pregnancy and lactation data were lacking. This void was often filled by misinformation. Even as data about pregnancy outcomes following COVID-19 vaccination began to emerge, the public was often unsure how to interpret the information, and many pregnant women remained unclear on whether to get vaccinated. MotherToBaby and Centers for Disease Control and Prevention (CDC) quickly partnered to direct the public to MotherToBaby, a nationwide teratogen information service, for free and confidential discussions about COVID-19 vaccines in pregnancy and lactation. This paper describes the partnership between MotherToBaby and CDC and the resulting COVID-19 vaccine inquiries received.

Methods

Aggregate, deidentified data were extracted from a centralized database utilized by MotherToBaby to capture information about exposure inquiries. The data include exposure topics, caller characteristics, and specific questions about COVID-19 vaccination.

Results

Between March 1, 2021 and February 28, 2023, MotherToBaby answered 11,064 questions about COVID-19 vaccines. Most (68.5%) were related to vaccine safety, with common safety-related themes including perceived haste in vaccine development, hesitancy about mRNA technology, and concerns about infertility, miscarriage, and long-term effects on the child. Lessons learned include the essential role of partnerships to educate the public during emergencies, the importance of building staff capacity during nonemergency times, and the need for one-on-one conversations to counter vaccine misinformation.

Conclusions

During the COVID-19 pandemic, MotherToBaby met a critical need by providing individualized, evidence-based information to the public. During future public health emergencies, teratogen information services are uniquely suited to provide unbiased information about the risks and benefits of vaccines and other exposures.

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母婴和疾病预防控制中心：合作为怀孕和哺乳期间的COVID-19疫苗咨询提供快速和个性化的响应

背景 2019 年冠状病毒病（COVID-19）疫苗上市之初，缺乏孕期和哺乳期数据。这一空白往往被错误信息所填补。即使有关接种 COVID-19 疫苗后妊娠结局的数据开始出现，公众也往往不知道如何解读这些信息，许多孕妇仍然不清楚是否要接种疫苗。母亲要宝宝"（MotherToBaby）与美国疾病控制和预防中心（CDC）迅速合作，引导公众前往 "母亲要宝宝"（MotherToBaby）--一个全国性的畸形儿信息服务机构，免费、保密地讨论孕期和哺乳期接种 COVID-19 疫苗的问题。本文介绍了 MotherToBaby 与疾病预防控制中心之间的合作以及由此收到的 COVID-19 疫苗咨询。方法从 MotherToBaby 使用的中央数据库中提取去身份化的汇总数据，以获取有关暴露咨询的信息。数据包括暴露主题、来电者特征以及有关 COVID-19 疫苗接种的具体问题。结果在 2021 年 3 月 1 日至 2023 年 2 月 28 日期间，MotherToBaby 共回答了 11,064 个有关 COVID-19 疫苗的问题。大多数问题（68.5%）与疫苗安全有关，常见的安全相关主题包括疫苗开发的仓促感、对 mRNA 技术的犹豫不决以及对不孕、流产和对儿童的长期影响的担忧。汲取的经验教训包括：在紧急情况下，合作伙伴在教育公众方面的重要作用；在非紧急情况下，员工能力建设的重要性；以及一对一对话以消除疫苗误导的必要性。结论在 COVID-19 大流行期间，"母亲为婴儿 "满足了公众的关键需求，为他们提供了个性化的循证信息。在未来的公共卫生突发事件中，畸形儿信息服务机构可以提供有关疫苗和其他暴露风险与益处的公正信息。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Birth Defects Research Medicine-Embryology

CiteScore

3.60

自引率

9.50%

发文量

153

期刊介绍： The journal Birth Defects Research publishes original research and reviews in areas related to the etiology of adverse developmental and reproductive outcome. In particular the journal is devoted to the publication of original scientific research that contributes to the understanding of the biology of embryonic development and the prenatal causative factors and mechanisms leading to adverse pregnancy outcomes, namely structural and functional birth defects, pregnancy loss, postnatal functional defects in the human population, and to the identification of prenatal factors and biological mechanisms that reduce these risks. Adverse reproductive and developmental outcomes may have genetic, environmental, nutritional or epigenetic causes. Accordingly, the journal Birth Defects Research takes an integrated, multidisciplinary approach in its organization and publication strategy. The journal Birth Defects Research contains separate sections for clinical and molecular teratology, developmental and reproductive toxicology, and reviews in developmental biology to acknowledge and accommodate the integrative nature of research in this field. Each section has a dedicated editor who is a leader in his/her field and who has full editorial authority in his/her area.