Clinical Efficacy of Acupuncture Therapy Based on the Principles of Primary Point Selection, Local Point Selection, and Syndrome Differentiation in Rheumatoid Arthritis

IF 2.4 4区医学 Q2 RHEUMATOLOGY

International Journal of Rheumatic Diseases Pub Date : 2025-04-23 DOI:10.1111/1756-185X.70226

Jun Zhao, Qiongxiao Wang, Shiyao Zhang, Longming Lei, Dahong Fang, Xiangqian Zhang, Xuebin Lu

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引用次数: 0

Abstract

Objective

To evaluate the clinical efficacy of acupuncture treatment based on the principles of primary point selection, local point selection, and syndrome differentiation in patients with rheumatoid arthritis (RA).

Methods

RA patients recruited from the rheumatology department of our hospital between January 2022 and January 2024 were randomly assigned to either the sham acupuncture group or the acupuncture group. The sham group received medication combined with sham acupuncture, while the acupuncture group received medication combined with acupuncture based on the principles above. Comparisons were made on Traditional Chinese Medicine (TCM) syndrome scores, quality of life, clinical symptoms, and inflammatory status after 4 weeks of treatment.

Results

A total of 65 patients in the acupuncture group and 66 in the sham group were analyzed. The acupuncture group showed a substantially higher total effective rate than the sham group, underscoring a significant advantage in treatment efficacy (81.56% vs. 60.61%). After treatment, the reduction in TCM syndrome scores in the acupuncture group was greater by 1.16 compared to the sham group (95% CI: 0.21–2.12). Following treatment, both groups showed notable improvements, as shown by notable decreases in their Disease Activity Score for 28 joints and Health Assessment Questionnaire ratings. The acupuncture group reported significantly lower scores than the sham group (all p < 0.05). Additionally, rheumatoid factor, high-sensitivity C-reactive protein, and erythrocyte sedimentation rate levels were decreased in both groups. All of the results were statistically significant (all p < 0.05). However, the acupuncture group had significantly lower levels of these markers than the sham group. This suggests that acupuncture has a stronger therapeutic impact when treating illness.

Conclusion

Acupuncture treatment based on primary point selection, local point selection, and syndrome differentiation significantly alleviates clinical symptoms and inflammatory states in patients with RA, thereby improving quality of life.

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基于始穴、局部、辨证原则的针灸治疗类风湿关节炎的临床疗效

目的评价以主穴选择、局部选穴、辨证论治为原则的针刺治疗对类风湿性关节炎（RA）患者的临床疗效。方法将 2022 年 1 月至 2024 年 1 月期间从我院风湿免疫科招募的 RA 患者随机分配到假针灸组或针灸组。假针灸组接受药物治疗和假针灸，而针灸组则根据上述原则接受药物治疗和针灸。治疗 4 周后，对中医综合征评分、生活质量、临床症状和炎症状况进行比较。结果对针灸组 65 名患者和假针灸组 66 名患者进行了分析。针灸组的总有效率大大高于假针灸组，显示出针灸在疗效上的显著优势（81.56% 对 60.61%）。治疗后，针灸组中医综合征评分的降低幅度比假组高 1.16（95% CI：0.21-2.12）。治疗后，两组患者的病情均有明显改善，28 个关节的疾病活动度评分和健康评估问卷评分均显著下降。针灸组的评分明显低于假针灸组（均为 p < 0.05）。此外，两组的类风湿因子、高敏 C 反应蛋白和红细胞沉降率水平均有所下降。所有结果均有统计学意义（均为 p <0.05）。然而，针灸组的这些指标水平明显低于假针灸组。这表明针灸在治疗疾病时具有更强的疗效。结论基于主穴选择、局部选穴和证候分型的针灸治疗可明显缓解 RA 患者的临床症状和炎症状态，从而提高生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Rheumatic Diseases RHEUMATOLOGY-

CiteScore

3.70

自引率

4.00%

发文量

362

审稿时长

1 months

期刊介绍： The International Journal of Rheumatic Diseases (formerly APLAR Journal of Rheumatology) is the official journal of the Asia Pacific League of Associations for Rheumatology. The Journal accepts original articles on clinical or experimental research pertinent to the rheumatic diseases, work on connective tissue diseases and other immune and allergic disorders. The acceptance criteria for all papers are the quality and originality of the research and its significance to our readership. Except where otherwise stated, manuscripts are peer reviewed by two anonymous reviewers and the Editor.