Microscopic analysis of a primo vessel within a lymphatic vessel in a Sprague-Dawley rat

Q3 Medicine

Translational Research in Anatomy Pub Date : 2025-04-13 DOI:10.1016/j.tria.2025.100402

Felix Scholkmann , Yiming Shen , Pan-Dong Ryu

引用次数: 0

Abstract

Background

Numerous studies have documented the existence of an additional vascular system in mammals: the primo vascular system (PVS), consisting of primo vessels (PVs) and primo nodes.

Methods

The PVS was investigated in five Sprague-Dawley rats. The dye Alcian blue was injected into the lymph node near the lumbar spine (lumbar lymph node) in one rat to stain the lymphatic tissue to determine whether the lymphatic vessels (LVs) contained PVs.

Results

A PV (diameter: ∼30–50 μm) inside a LV (diameter: ∼120–200 μm) was identified near the inferior vena cava. Microscopy images of this specimen are shown in this report and analysed. A reference is given to a detailed guide on how to find, extract and analyse the PVs within the LVs of rats.

Conclusions

The case report documents a PV inside an LV and shows that LVs can contain a secondary vessel that could be identified as a PV and part of the PVS.

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Sprague-Dawley大鼠淋巴管内第一血管的显微分析

大量研究已经证明哺乳动物存在一个额外的血管系统：原始血管系统（primo vascular system， PVS），由原始血管（primo vessel, pv）和原始淋巴结组成。方法对5只sd大鼠进行PVS观察。将阿利新蓝染色剂注射到一只大鼠腰椎附近的淋巴结（腰椎淋巴结），对淋巴组织进行染色，以确定淋巴管（lv）中是否含有pv。结果在下腔静脉附近发现了直径约为120 ~ 200 μm的LV内的sa PV（直径约为30 ~ 50 μm）。本报告显示了该标本的显微镜图像并进行了分析。本文给出了如何在大鼠LVs中找到、提取和分析pv的详细指南。该病例报告记录了左室内的PV，并表明左室可包含可识别为PV和PVS一部分的第二血管。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Translational Research in Anatomy Medicine-Anatomy

CiteScore

2.90

自引率

0.00%

发文量

审稿时长

25 days

期刊介绍： Translational Research in Anatomy is an international peer-reviewed and open access journal that publishes high-quality original papers. Focusing on translational research, the journal aims to disseminate the knowledge that is gained in the basic science of anatomy and to apply it to the diagnosis and treatment of human pathology in order to improve individual patient well-being. Topics published in Translational Research in Anatomy include anatomy in all of its aspects, especially those that have application to other scientific disciplines including the health sciences: • gross anatomy • neuroanatomy • histology • immunohistochemistry • comparative anatomy • embryology • molecular biology • microscopic anatomy • forensics • imaging/radiology • medical education Priority will be given to studies that clearly articulate their relevance to the broader aspects of anatomy and how they can impact patient care.Strengthening the ties between morphological research and medicine will foster collaboration between anatomists and physicians. Therefore, Translational Research in Anatomy will serve as a platform for communication and understanding between the disciplines of anatomy and medicine and will aid in the dissemination of anatomical research. The journal accepts the following article types: 1. Review articles 2. Original research papers 3. New state-of-the-art methods of research in the field of anatomy including imaging, dissection methods, medical devices and quantitation 4. Education papers (teaching technologies/methods in medical education in anatomy) 5. Commentaries 6. Letters to the Editor 7. Selected conference papers 8. Case Reports