Associations between parental vaccine hesitancy, religion-based vaccine hesitancy, and childhood full vaccination in a cross-sectional study in Aceh, Indonesia, 2023

IF 4.5 3区医学 Q2 IMMUNOLOGY

Vaccine Pub Date : 2025-04-24 DOI:10.1016/j.vaccine.2025.127154

Jacob Jacovetty , Abram L. Wagner , Ichsan Ichsan , Amanda Yufika , Tita Menawati , Rosaria Indah , Fitdha Kairadini , Antonios M. Koumpias , Harapan Harapan

{"title":"Associations between parental vaccine hesitancy, religion-based vaccine hesitancy, and childhood full vaccination in a cross-sectional study in Aceh, Indonesia, 2023","authors":"Jacob Jacovetty , Abram L. Wagner , Ichsan Ichsan , Amanda Yufika , Tita Menawati , Rosaria Indah , Fitdha Kairadini , Antonios M. Koumpias , Harapan Harapan","doi":"10.1016/j.vaccine.2025.127154","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Many Muslims in Indonesia have religion-based concerns surrounding vaccine ingredients. The aim of this study was to examine the correlation between parental religion-based vaccine hesitancy and other types of vaccine hesitancy, and to assess the association between parental vaccine hesitancy, religion-based vaccine hesitancy, and childhood full vaccination.</div></div><div><h3>Methods</h3><div>This study was based on a multistage, cluster sample within in Aceh, Indonesia. The survey included demographic characteristics, measures of vaccine hesitancy, structural barriers, and vaccination status questions. We examined correlations using Pearson correlation coefficient and the relationship between vaccine hesitancy, and religion-based vaccine concerns, on a child being fully vaccinated using a Poisson regression model with robust variance estimation.</div></div><div><h3>Results</h3><div>The study included 1689 participants and all were Muslim. Only 34 % of children were fully vaccinated, 29 % of parents were vaccine hesitant, and 32 % expressed concerns that vaccine ingredients were not halal. Childhood vaccination status, vaccine hesitancy, and religion-based concerns were all significantly correlated with each other. In a multivariable model, vaccine hesitancy and religion-based concerns were both directly significant in their relationship with childhood vaccination status. Those who were vaccine hesitant were only 0.21 times as likely to have a child fully vaccinated compared to those not hesitant (95 % CI: 0.16, 0.37). Those with concerns about vaccine ingredients being halal also were less likely to have a child fully vaccinated (PR: 0.55, 95 % CI: 0.42, 0.72).</div></div><div><h3>Conclusion</h3><div>We found that religious-based vaccine concerns were highly prominent in this population, and likely a large contributor to vaccine hesitancy. Efforts to improve vaccination coverage should focus on addressing religious concerns and working closely with religious leaders to build trust and disseminate accurate information about vaccines.</div></div>","PeriodicalId":23491,"journal":{"name":"Vaccine","volume":"56 ","pages":"Article 127154"},"PeriodicalIF":4.5000,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Vaccine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0264410X25004517","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"IMMUNOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Many Muslims in Indonesia have religion-based concerns surrounding vaccine ingredients. The aim of this study was to examine the correlation between parental religion-based vaccine hesitancy and other types of vaccine hesitancy, and to assess the association between parental vaccine hesitancy, religion-based vaccine hesitancy, and childhood full vaccination.

Methods

This study was based on a multistage, cluster sample within in Aceh, Indonesia. The survey included demographic characteristics, measures of vaccine hesitancy, structural barriers, and vaccination status questions. We examined correlations using Pearson correlation coefficient and the relationship between vaccine hesitancy, and religion-based vaccine concerns, on a child being fully vaccinated using a Poisson regression model with robust variance estimation.

Results

The study included 1689 participants and all were Muslim. Only 34 % of children were fully vaccinated, 29 % of parents were vaccine hesitant, and 32 % expressed concerns that vaccine ingredients were not halal. Childhood vaccination status, vaccine hesitancy, and religion-based concerns were all significantly correlated with each other. In a multivariable model, vaccine hesitancy and religion-based concerns were both directly significant in their relationship with childhood vaccination status. Those who were vaccine hesitant were only 0.21 times as likely to have a child fully vaccinated compared to those not hesitant (95 % CI: 0.16, 0.37). Those with concerns about vaccine ingredients being halal also were less likely to have a child fully vaccinated (PR: 0.55, 95 % CI: 0.42, 0.72).

Conclusion

We found that religious-based vaccine concerns were highly prominent in this population, and likely a large contributor to vaccine hesitancy. Efforts to improve vaccination coverage should focus on addressing religious concerns and working closely with religious leaders to build trust and disseminate accurate information about vaccines.

查看原文本刊更多论文

在2023年印度尼西亚亚齐的一项横断面研究中，父母疫苗犹豫、基于宗教的疫苗犹豫和儿童全面疫苗接种之间的关系

印度尼西亚的许多穆斯林对疫苗成分有基于宗教的担忧。本研究的目的是检验父母基于宗教信仰的疫苗犹豫与其他类型的疫苗犹豫之间的相关性，并评估父母基于宗教信仰的疫苗犹豫与儿童全面接种疫苗之间的关系。方法本研究基于印度尼西亚亚齐省的多阶段整群样本。该调查包括人口统计学特征、疫苗犹豫措施、结构性障碍和疫苗接种状况问题。我们使用具有稳健方差估计的泊松回归模型，使用Pearson相关系数和疫苗犹豫与基于宗教的疫苗关注之间的关系来检验儿童完全接种疫苗的相关性。结果这项研究包括1689名参与者，他们都是穆斯林。只有34%的儿童完全接种了疫苗，29%的父母对疫苗接种犹豫不决，32%的人表示担心疫苗成分不清真。儿童疫苗接种状况、疫苗犹豫和基于宗教的担忧均显著相关。在多变量模型中，疫苗犹豫和基于宗教的担忧在与儿童疫苗接种状况的关系中都具有直接意义。与不犹豫的儿童相比，犹豫不决的儿童完全接种疫苗的可能性仅为0.21倍（95% CI: 0.16, 0.37）。那些担心疫苗成分是清真的人也不太可能让孩子完全接种疫苗（PR: 0.55, 95% CI: 0.42, 0.72）。结论：我们发现基于宗教的疫苗担忧在这一人群中非常突出，并且可能是疫苗犹豫的主要原因。提高疫苗接种覆盖率的努力应侧重于解决宗教关切，并与宗教领袖密切合作，建立信任并传播有关疫苗的准确信息。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Vaccine 医学-免疫学

CiteScore

8.70

自引率

5.50%

发文量

992

审稿时长

131 days

期刊介绍： Vaccine is unique in publishing the highest quality science across all disciplines relevant to the field of vaccinology - all original article submissions across basic and clinical research, vaccine manufacturing, history, public policy, behavioral science and ethics, social sciences, safety, and many other related areas are welcomed. The submission categories as given in the Guide for Authors indicate where we receive the most papers. Papers outside these major areas are also welcome and authors are encouraged to contact us with specific questions.