{"title":"Shaping the future of the IVF laboratory: standardization for more predictable outcomes","authors":"Mina Alikani , Alison Campbell","doi":"10.1016/j.rbmo.2025.104854","DOIUrl":null,"url":null,"abstract":"<div><div>IVF is the foundational technology in the broader field of assisted reproductive technology (ART). The IVF laboratory is at the heart of ART, both as a major source of innovation and advancement and as a key to the success of the treatments. However, substantial variability in laboratory practices persists, despite longstanding efforts to establish uniform standards for improved reliability, reproducibility, and comparability. This commentary highlights the core factors contributing to disparity in outcomes and illustrates how emerging technologies, particularly artificial intelligence and robotics, offer new opportunities to propel standardization forwards. By integrating data-driven benchmarks and automated processes, including in quality management, the future IVF laboratory can achieve better and more predictable outcomes and advance the global standard of care.</div></div>","PeriodicalId":21134,"journal":{"name":"Reproductive biomedicine online","volume":"50 4","pages":"Article 104854"},"PeriodicalIF":3.7000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Reproductive biomedicine online","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1472648325000616","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
IVF is the foundational technology in the broader field of assisted reproductive technology (ART). The IVF laboratory is at the heart of ART, both as a major source of innovation and advancement and as a key to the success of the treatments. However, substantial variability in laboratory practices persists, despite longstanding efforts to establish uniform standards for improved reliability, reproducibility, and comparability. This commentary highlights the core factors contributing to disparity in outcomes and illustrates how emerging technologies, particularly artificial intelligence and robotics, offer new opportunities to propel standardization forwards. By integrating data-driven benchmarks and automated processes, including in quality management, the future IVF laboratory can achieve better and more predictable outcomes and advance the global standard of care.
期刊介绍:
Reproductive BioMedicine Online covers the formation, growth and differentiation of the human embryo. It is intended to bring to public attention new research on biological and clinical research on human reproduction and the human embryo including relevant studies on animals. It is published by a group of scientists and clinicians working in these fields of study. Its audience comprises researchers, clinicians, practitioners, academics and patients.
Context:
The period of human embryonic growth covered is between the formation of the primordial germ cells in the fetus until mid-pregnancy. High quality research on lower animals is included if it helps to clarify the human situation. Studies progressing to birth and later are published if they have a direct bearing on events in the earlier stages of pregnancy.