A focused review of saliva biomarkers in cognitive fatigue: Current challenges and future directions

IF 3.6 2区 医学 Q2 ENDOCRINOLOGY & METABOLISM
Yunxian Pan
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引用次数: 0

Abstract

This study provides a focused review on the use of saliva biomarkers, particularly salivary cortisol, for measuring cognitive fatigue. Through a systematic review and analysis of 25 articles sourced from five academic databases, we examine the relationship between cognitive fatigue and saliva biomarkers. The findings highlight the potential of salivary cortisol as an effective marker of cognitive fatigue, while also identifying limitations in current methodologies, including inconsistent saliva collection and analysis procedures. Although prior reviews have explored saliva biomarkers, our analysis focuses on gaps related to the empirical connection between cognitive fatigue and biomarkers. This review further meta-analysis reveals that cortisol and alpha-amylase levels significantly increased after completing cognitive fatigue-inducing tasks. Moreover, this review emphasizes the need for updated, standardized protocols and real-time detection methods. Future research should aim to conduct more focused empirical investigations to advance the field.
唾液生物标志物在认知疲劳中的研究综述:当前的挑战和未来的方向
本研究对使用唾液生物标志物,特别是唾液皮质醇来测量认知疲劳进行了重点综述。通过系统回顾和分析来自五个学术数据库的25篇文章,我们研究了认知疲劳和唾液生物标志物之间的关系。研究结果强调了唾液皮质醇作为认知疲劳有效标志的潜力,同时也指出了当前方法的局限性,包括不一致的唾液收集和分析程序。虽然之前的综述已经探讨了唾液生物标志物,但我们的分析侧重于认知疲劳与生物标志物之间的经验联系相关的空白。本综述进一步的荟萃分析显示,皮质醇和α -淀粉酶水平在完成认知疲劳诱导任务后显著增加。此外,本综述强调需要更新,标准化的协议和实时检测方法。未来的研究应着眼于进行更有针对性的实证调查,以推动该领域的发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Psychoneuroendocrinology
Psychoneuroendocrinology 医学-精神病学
CiteScore
7.40
自引率
8.10%
发文量
268
审稿时长
66 days
期刊介绍: Psychoneuroendocrinology publishes papers dealing with the interrelated disciplines of psychology, neurobiology, endocrinology, immunology, neurology, and psychiatry, with an emphasis on multidisciplinary studies aiming at integrating these disciplines in terms of either basic research or clinical implications. One of the main goals is to understand how a variety of psychobiological factors interact in the expression of the stress response as it relates to the development and/or maintenance of neuropsychiatric illnesses.
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